Healthcare resource utilization and costs among patients with direct oral anticoagulant or warfarin-related major bleeding

摘要

Introduction: Direct oral anticoagulants (DOACs) have expanded the options for antithrombotic therapy. DOAC-related major bleeds are associated with favorable outcomes compared to warfarin in clinical trials and routine practice. However, it is unclear whether management of DOAC-associated major bleeding incurs higher resource utilization and costs.