Safety, Tolerability and Pharmacokinetics of MEDI8897, an Extended Half-life Single-dose Respiratory Syncytial Virus Prefusion F-targeting Monoclonal Antibody Administered as a Single Dose to Healthy Preterm Infants

Domachowske Joseph B.; Khan Anis A.; Esser Mark T.; Jensen Kathryn; Takas Therese; Villafana Tonya; Dubovsky Filip; Griffin M. Pamela

首页> 外文期刊>The Pediatric infectious disease journal >Safety, Tolerability and Pharmacokinetics of MEDI8897, an Extended Half-life Single-dose Respiratory Syncytial Virus Prefusion F-targeting Monoclonal Antibody Administered as a Single Dose to Healthy Preterm Infants

【24h】

Safety, Tolerability and Pharmacokinetics of MEDI8897, an Extended Half-life Single-dose Respiratory Syncytial Virus Prefusion F-targeting Monoclonal Antibody Administered as a Single Dose to Healthy Preterm Infants

机译：Medi8897的安全性，耐受性和药代动力学，延伸半衰期单剂量呼吸合胞病毒预防F靶向单克隆抗体作为单剂量给健康的早产儿

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Background: MEDI8897 is a recombinant human monoclonal antibody being developed for prophylaxis of serious respiratory syncytial virus (RSV) disease in all infants.

机译：背景：Medi8897是一种重组人单克隆抗体，用于所有婴儿的严重呼吸道合胞病毒（RSV）疾病的预防。

著录项

来源
《The Pediatric infectious disease journal》 |2018年第9期|共7页
作者
Domachowske Joseph B.; Khan Anis A.; Esser Mark T.; Jensen Kathryn; Takas Therese; Villafana Tonya; Dubovsky Filip; Griffin M. Pamela;
展开▼
作者单位

SUNY Upstate Med Univ Div Infect Dis Dept Pediat Syracuse NY 13210 USA;

MedImmune Astra Zeneca Gaithersburg MD USA;

MedImmune Astra Zeneca Gaithersburg MD USA;

MedImmune Astra Zeneca Gaithersburg MD USA;

MedImmune Astra Zeneca Gaithersburg MD USA;

MedImmune Astra Zeneca Gaithersburg MD USA;

MedImmune Astra Zeneca Gaithersburg MD USA;

MedImmune Astra Zeneca Gaithersburg MD USA;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类儿科学;
关键词
infants; lower respiratory tract infections; MEDI8897; preterm infants; respiratory syncytial virus;

机译：婴儿;降低呼吸道感染;Medi8897;早产儿;呼吸道合胞病毒;

相似文献

外文文献
中文文献

1. Safety, Tolerability and Pharmacokinetics of MEDI8897, an Extended Half-life Single-dose Respiratory Syncytial Virus Prefusion F-targeting Monoclonal Antibody Administered as a Single Dose to Healthy Preterm Infants [J] . Domachowske Joseph B., Khan Anis A., Esser Mark T., The Pediatric infectious disease journal . 2018,第9期

机译：Medi8897的安全性，耐受性和药代动力学，延伸半衰期单剂量呼吸合胞病毒预防F靶向单克隆抗体作为单剂量给健康的早产儿
2. Safety, Tolerability and Pharmacokinetics of MEDI8897, an Extended Half-life Single-dose Respiratory Syncytial Virus Prefusion F-targeting Monoclonal Antibody Administered as a Single Dose to Healthy Preterm Infants [J] . Domachowske Joseph B., Khan Anis A., Esser Mark T., The Pediatric infectious disease journal . 2018,第9期

机译：Medi8897的安全性，耐受性和药代动力学，延伸半衰期单剂量呼吸合胞病毒预防F靶向单克隆抗体作为单剂量给健康的早产儿
3. Population pharmacokinetic modeling of MEDI8897, an extended half-life monoclonal antibody (mAb), and dose prediction in preterm and full-term infants to prevent lower respiratory tract infection due to respiratory syncytial virus (RSV) [J] . Pierre Vadryn, Griffin M. Pamela, Shoemaker Kathryn, Journal of pharmacokinetics and pharmacodynamics . 2018,第Suppla期

机译：Medi8897的人口药代动力学建模，延长半衰期单克隆抗体（MAB），以及预料和全初期婴儿的剂量预测，以防止呼吸合胞病毒（RSV）引起的呼吸道感染
4. Pharmacokinetics and Tolerability of Sublingual Fentanyl in Healthy Japanese and Caucasian Volunteers: Phase I, Open-Label Single-Dose Study [C] . U. Lorch, F. Farrell, J. Kilborn, International Pain Clinic Congress . 2008

机译：健康日本和白种人志愿者舌下芬太尼的药代动力学和耐受性：I期，开放标签单剂量研究
5. Safety Tolerability and Pharmacokinetics of MEDI8897 an Extended Half-life Single-dose Respiratory Syncytial Virus Prefusion F-targeting Monoclonal Antibody Administered as a Single Dose to Healthy Preterm Infants [O] . Joseph B. Domachowske, Anis A. Khan, Mark T. Esser, -1

机译：MEDI8897的安全性耐受性和药代动力学这是一种延长剂量的针对健康早产婴儿的半衰期单剂量呼吸道合胞病毒预融合F靶向单克隆抗体
6. Safety, Tolerability and Pharmacokinetics of MEDI8897, an Extended Half-life Single-dose Respiratory Syncytial Virus Prefusion F-targeting Monoclonal Antibody Administered as a Single Dose to Healthy Preterm Infants [O] . Joseph B. Domachowske, Anis A. Khan, Mark T. Esser, 2018

机译：Medi8897的安全性，耐受性和药代动力学，延伸半衰期单剂量呼吸合胞病毒预防F靶向单克隆抗体作为单剂量给健康早产儿

Safety, Tolerability and Pharmacokinetics of MEDI8897, an Extended Half-life Single-dose Respiratory Syncytial Virus Prefusion F-targeting Monoclonal Antibody Administered as a Single Dose to Healthy Preterm Infants

摘要

著录项

相似文献

相关主题

期刊订阅