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Timing of Referral of Patients With Severe Isolated Tricuspid Valve Regurgitation to Surgeons (from a French Nationwide Database)

机译:严重孤立的三尖瓣瓣膜瓣转诊到外科医生(来自法国全国数据库)的时序

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摘要

Series evaluating the results of isolated tricuspid valve surgery (ITVS) are rare and often limited by small sample size, selection bias, and/or long period of enrollment. Based on a mandatory administrative national database, we collected all consecutive ITVS performed in France during a 2-year period (2013 and 2014), the type of intervention, clinical profile, and in-hospital mortality and complications. During the 2-year period, 241 patients underwent an ITVS in France (84 repairs and 157 replacements). In-hospital mortality was high (10%), and most patients experienced at least 1 complication (65%) with a 19% rate of major complications (death, need for dialysis, or need for mechanical support using extracorporeal membrane oxygenation). Consequently, hospital duration was remarkably long (26 40 days). Congestive heart failure at presentation was associated with mortality and major complications rates (both p = 0.01). In conclusion, in a contemporary and consecutive series, ITVS was associated with a high mortality and morbidity predicted by clinical presentation at baseline. Our results suggest that patients are often referred too late and that an earlier intervention may improve immediate and possibly midterm outcomes. With the availability of transcatheter therapies in a near future, optimal timing of intervention in this population will be of utmost importance. (C) 2018 Elsevier Inc. All rights reserved.
机译:系列评估分离的三尖瓣手术(ITV)的结果是罕见的,通常受到小样本大小,选择偏差和/或长期注册的限制。根据强制性行政国家数据库,我们在2年期间(2013年和2014年),干预类型,临床概况和医院内死亡和并发症中所有连续ITV收集所有连续ITV。在2年期间,241名患者在法国进行ITV(84台和157个替代品)。在医院的死亡率高(10%),大多数患者至少经历了至少1个并发症(65%)(65%),主要并发症率为19%(死亡,需要透析,或者使用体外膜氧合的机械载体)。因此,医院持续时间非常长(260天)。呈现的充血性心力衰竭与死亡率和主要并发症率(P = 0.01)有关。总之,在当代和连续的系列中,ITV与基线临床介绍预测的高死亡率和发病率有关。我们的研究结果表明,患者往往是为时已晚的,并且早期干预可能会改善立即和可能的中期结果。随着经沟管疗法在不久的将来的情况下,本人干预的最佳时间将是至关重要的。 (c)2018年Elsevier Inc.保留所有权利。

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