Interferon-stimulated gene 15 (ISG15) restricts Zika virus replication in primary human corneal epithelial cells

Singh Pawan Kumar; Singh Sneha; Farr Dustin; Kumar Ashok

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Interferon-stimulated gene 15 (ISG15) restricts Zika virus replication in primary human corneal epithelial cells

机译：干扰素刺激的基因15（ISG15）限制了原发性人角膜上皮细胞中的Zika病毒复制

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Purpose: Zika virus (ZIKV) has emerged as an important human pathogen causing ocular complications. There have been reports of the shedding of ZIKV in human as well as animal tears. In this study, we investigated the infectivity of ZIKV in corneal epithelial cells and their antiviral immune response.

机译：目的：Zika病毒（ZIKV）已成为引起眼部并发症的重要人体病原体。已经有报道ZIKV在人类和动物泪水中的缩小。在这项研究中，我们研究了ZIKV在角膜上皮细胞中的感染性及其抗病毒免疫反应。

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来源
《The ocular surface 》 |2019年第3期| 共9页
作者
Singh Pawan Kumar; Singh Sneha; Farr Dustin; Kumar Ashok;
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作者单位

Wayne State Univ Dept Ophthalmol Visual &

Anat Sci Detroit MI 48201 USA;

Wayne State Univ Dept Ophthalmol Visual &

Anat Sci Detroit MI 48201 USA;

Wayne State Univ Dept Biochem Microbiol &

Immunol Detroit MI 48201 USA;

Wayne State Univ Dept Ophthalmol Visual &

Anat Sci Detroit MI 48201 USA;

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原文格式 PDF
正文语种 eng
中图分类眼科学 ;
关键词
Antiviral; Cornea; Dengue virus; Innate immune response; ISG15; Zika virus;

机译：抗病毒;角膜;登革热病毒;天生的免疫反应;ISG15;ZIKA病毒;

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专利

1. Interferon-stimulated gene 15 (ISG15) restricts Zika virus replication in primary human corneal epithelial cells [J] . Singh Pawan Kumar, Singh Sneha, Farr Dustin, The ocular surface . 2019 ,第3期

机译：干扰素刺激的基因15（ISG15）限制了原发性人角膜上皮细胞中的Zika病毒复制
2. Isolation and genetic characterization of human coronavirus NL63 in primary human renal proximal tubular epithelial cells obtained from a commercial supplier, and confirmation of its replication in two different types of human primary kidney cells [J] . John A Lednicky, Thomas B Waltzek, Elizabeth McGeehan, Virology Journal . 2013 ,第1期

机译：从商业供应商处获得的人冠状病毒NL63在人原代肾近端肾小管上皮细胞中的分离和遗传特性，并证实其在两种不同类型的人原代肾细胞中的复制
3. Positive Feedback Loop of Long Noncoding RNA OASL-IT1 and Innate Immune Response Restricts the Replication of Zika Virus in Epithelial A549 Cells [J] . Wang Y., Huo Z., Lin Q., Journal of innate immunity . 2021 ,第3期

机译：长度非数性RNA OASL-IT1和先天免疫应答的正反馈环限制了Zika病毒在上皮A549细胞中的复制
4. Dendrimer crosslinked collagen hydrogels modified with YIGSR peptide and their effects on cellular behaviors of human corneal epithelial cell line and nerve regeneration [C] . Duan, X, McLaughlin, Society for Biomaterials Transaction Annual Meeting vol.29 pt.2 . 2006

机译：YIGSR肽修饰的树状聚合物交联胶原水凝胶及其对人角膜上皮细胞系细胞行为和神经再生的影响
5. Replication of neurovirulent and non-neurovirulent human H1N1 influenza A viruses in mouse brain and nerve cell cultures: Virus strain-specific and host cell-dependent variations in progeny virus assembly,mRNA splicing efficiency, and expression of RNA gene segments 7 and 8 [D] . Husak, Paul James 1994

机译：在鼠脑和神经细胞培养物中复制神经毒力和非神经毒力的人类甲型H1N1流感病毒：子代病毒装配，mRNA剪接效率以及RNA基因片段7和8的表达中病毒株特异性和宿主细胞依赖性变异
6. Regulation of Interferon-stimulated Gene (ISG)12 ISG15 and MX1 and MX2 by Conceptus Interferons (IFNTs) in Bovine Uterine Epithelial Cells [O] . Min-Su Kim, Kwan-Sik Min, Kazuhiko Imakawa 2013

机译：牛子宫上皮细胞中的概念干扰素（IFNT）对干扰素刺激基因（ISG）12ISG15和MX1和MX2的调节
7. Interferon-stimulated gene 15 (ISG15) restricts Zika virus replication in primary human corneal epithelial cells [O] . Pawan Kumar Singh, Sneha Singh, Dustin Farr, 2019

机译：干扰素刺激的基因15（ISG15）限制了原发性人角膜上皮细胞中的Zika病毒复制

Interferon-stimulated gene 15 (ISG15) restricts Zika virus replication in primary human corneal epithelial cells

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