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首页> 外文期刊>Advances in therapy. >Comparison of carotid artery stenting and carotid endarterectomy in patients with symptomatic carotid artery stenosis: A single center study
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Comparison of carotid artery stenting and carotid endarterectomy in patients with symptomatic carotid artery stenosis: A single center study

机译:有症状的颈动脉狭窄患者的颈动脉支架置入术和颈动脉内膜切除术的比较:单中心研究

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Introduction: Carotid artery stenting (CAS) is believed to be an alternative to carotid endarterectomy (CEA); however, recent studies have demonstrated an increase of complications with stenting that does not reflect our experience. We thus wanted to compare the periprocedural and 1-year follow-up outcomes of CAS with those of CEA among patients with symptomatic extracranial carotid stenosis in a population from eastern Turkey. Methods: The hospital records of all patients who underwent carotid artery revascularization were retrospectively reviewed. Patients were divided into two groups based on the type of carotid revascularization performed, namely CEA or CAS. Comparisons were made with respect to 30-day and 1-year outcomes of transient ischemic attack (TIA), myocardial infarction (MI), stroke, and all-cause death rates. Composite endpoints for both groups were also analyzed. Results: Thirty-two CEA and 33 CAS procedures were performed for symptomatic occlusive carotid disease. Baseline characteristics were similar between both groups except for the incidence of diabetes mellitus. No significant differences were found with respect to 30-day mortality, MI, and neurologic morbidity endpoints for CEA and CAS procedures. In the postprocedural 1-year follow-up, only TIA was observed to be significantly higher in the CAS group; the other endpoints did not differ significantly. One-year composite endpoints did not differ between both groups (log-rank P = 0.300). Conclusion: In our trial of patients with symptomatic carotid artery stenosis, no significant difference could be shown in periprocedural outcomes, postprocedural outcomes except TIA, and in composite endpoints between the CEA and CAS groups. CAS is a safe and efficacious alternative for the treatment of symptomatic carotid artery stenosis.
机译:简介:颈动脉支架置入术(CAS)被认为是颈动脉内膜切除术(CEA)的替代方法。但是,最近的研究表明,支架置入术并发症的增加没有反映我们的经验。因此,我们希望比较土耳其东部人群有症状的颅外颈动脉狭窄患者的CAS围手术期和1年随访结果与CEA的结局。方法:回顾性分析所有接受颈动脉血运重建术的患者的病历。根据所进行的颈动脉血运重建的类型将患者分为两组,即CEA或CAS。对短暂性脑缺血发作(TIA),心肌梗塞(MI),中风和全因死亡率的30天和1年结局进行了比较。两组的综合终点也进行了分析。结果:对有症状的闭塞性颈动脉疾病进行了32次CEA和33次CAS手术。除糖尿病的发生率外,两组的基线特征相似。在CEA和CAS手术的30天死亡率,MI和神经系统疾病终点方面,没有发现显着差异。在术后1年的随访中,CAS组仅观察到TIA明显高于对照组。其他端点没有显着差异。两组的一年综合终点没有差异(log-rank P = 0.300)。结论:在我们对有症状的颈动脉狭窄患者进行的试验中,CEA和CAS组之间的围手术期结局,除TIA外的术后结局以及复合终点均无显着差异。 CAS是治疗有症状的颈动脉狭窄的一种安全有效的替代方法。

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