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Prevalence and predictors of vitamin D deficiency in a nationally representative sample of adults participating in the 2011–2013 Australian Health Survey

机译:参与2011-2013澳大利亚卫生调查的全国成人国家代表性样本中维生素D缺乏的患病率和预测

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摘要

Vitamin D deficiency is recognised as a public health problem globally, and a high prevalence of deficiency has previously been reported in Australia. This study details the prevalence of vitamin D deficiency in a nationally representative sample of Australian adults aged ≥25 years, using an internationally standardised method to measure serum 25-hydroxyvitamin D (25(OH)D) concentrations and identifies demographic and lifestyle factors associated with vitamin D deficiency. We used data from the 2011–2013 Australian Health Survey (n 5034 with complete information on potential predictors and serum 25(OH)D concentrations). Serum 25(OH)D concentrations were measured by a liquid chromatography-tandem MS that is certified to the reference measurement procedures developed by the National Institute of Standards and Technology, Ghent University and the US Centers for Disease Control and Prevention. Vitamin D deficiency and insufficiency were defined as serum 25(OH)D concentrations 50 nmol/l and 50 to 75 nmol/l, respectively. Overall, 20 % of participants (19 % men; 21 % women) were classified as vitamin D deficient, with a further 43 % classified as insufficient (45 % men; 42 % women). Independent predictors of vitamin D deficiency included being born in a country other than Australia or the main English-speaking countries, residing in southern (higher latitude) states of Australia, being assessed during winter or spring, being obese, smoking (women only), having low physical activity levels and not taking vitamin D or Ca supplements. Given our increasingly indoor lifestyles, there is a need to develop and promote strategies to maintain adequate vitamin D status through safe sun exposure and dietary approaches.
机译:维生素D缺乏在全球公共健康问题被认为是澳大利亚的缺乏率高。本研究详细介绍了维生素D缺乏在澳大利亚成年人的国家代表性样本中的患病率,使用国际标准化的方法测量血清25-羟基维生素D(25(OH)D)浓度,并确定与之相关的人口和生活方式因素维生素D缺乏症。我们使用来自2011-2013澳大利亚健康调查的数据(N 5034,具有关于潜在预测因子和血清25(OH)D浓度的完整信息)。通过液相色谱 - 串联MS测量血清25(OH)D浓度,该液相色谱 - 串联MS被认证到国家标准和技术研究所,根特大学和美国疾病控制和预防中心开发的参考测量程序。维生素D缺乏症和不足的含量分别定义为血清25(OH)D浓度<50nmol / L和50至75苯酚/ L.总体而言,20%的参与者(19%的男性; 21%的女性)被归类为维生素D缺乏,另外43%分为43%,归类为不足(45%的男性; 42%的女性)。维生素D缺乏的独立预测因素包括在澳大利亚以外的国家/地区出生,居住在澳大利亚南部(高纬度)国家,在冬季或春季进行评估,肥胖,吸烟(仅限女性),具有低的身体活性水平,不服用维生素D或CA补充剂。鉴于我们越来越多的生活方式,需要通过安全的阳光照射和饮食方法来发展和促进维持足够的维生素D状态的策略。

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