DOES LATE GADOLINIUM ENHANCEMENT IDENTIFY THE PATIENTS AT RISK IN CHILDHOOD HYPERTROPHIC CARDIOMYOPATHY? A MULTICENTER STUDY

摘要

BACKGROUND: Cardiovascular magnetic resonance (CMR) with late gadolinium enhancement (LGE) has emerged as a potential marker for risk of adverse events in adult patients with hypertrophic cardiomyopathy (HCM). However, previous studies of pediatric patients have been limited to small cohorts with short follow-up periods and therefore the clinical significance of LGE in the pediatric HCM population remains uncertain. The aims of this study were 1) to quantify the prevalence and amount of LGE in an unse-lected pediatric population with HCM and 2) to assess the relation between LGE and ventricular arrhythmia, episodes of circulatory collapse, sudden cardiac death (SCD), and degree of heart failure at the time of MRI and during follow-up.