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Adjuvant treatment and survival in older women with triple negative breast cancer: A Surveillance, Epidemiology, and End Results analysis

机译:三重阴性乳腺癌的老年女性的佐剂治疗和生存:监测,流行病学和最终结果分析

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Abstract Patients with triple negative breast cancer were identified using the Surveillance, Epidemiology, and End Results database. Competing risks analysis was used to assess the cumulative incidence of breast cancer‐specific mortality (BCSM). Multivariable Fine‐Gray regression was used to identify predictors of BCSM. Women age 70+ (n?=?4221) were less likely to receive chemotherapy and radiation treatment ( P ??0.0001) and had higher BCSM compared to younger women ( P ??0.0001). There were no differences in BCSM in patients who received adjuvant treatment ( P ?=?0.10). Stage II patients derived the greatest relative and absolute benefit from adjuvant treatment. Age was not a significant predictor of BCSM.
机译:使用监测,流行病学和最终结果数据库鉴定了三重阴性乳腺癌的抽象患者。 竞争风险分析用于评估乳腺癌特异性死亡率(BCSM)的累积发病率。 多变量细灰色回归用于识别BCSM的预测因子。 女性70岁以上(N?=β2221)不太可能接受化疗和放射治疗(p≤≤0.0001)并与较小的女性相比具有更高的BCSM(P?& 0.0001)。 接受佐剂治疗的患者中BCSM没有差异(P?= 0.10)。 阶段II患者从佐剂治疗中获得最大的相对和绝对益处。 年龄不是BCSM的重要预测因素。

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