Solubilization and Thermodynamic Attributes of Nickel Phenanthroline Complex in Micellar Media of Sodium 2-Ethyl Hexyl Sulfate and Sodium Bis(2-ethyl hexyl) Sulfosuccinate

摘要

Micellar solubilization and physicochemical behaviour of [Ni(phen)(3)]F-2 EtOH center dot MeOH center dot 8 H2O complex in sodium 2-ethylhexyl sulfate and sodium bis(2-ethyl hexyl) sulfosuccinate is addressed in this paper. The interactions of surfactants in the solution of nickel complex were studied by UV-Vis spectroscopy and electrical conductivity. The extent of solubilization in terms of partitioning and binding parameters was determined by UV-Vis spectroscopy, whereas conductivity data were employed to calculate critical micellar concentration and other thermodynamic parameters of micellization. The value of critical micellar concentration increased in both surfactants due to structure breaking effect of nickel complex. The complex showed significant antioxidant radical scavenging and hemolytic activities, without any substantial cytotoxic activity against 3T3 cell line.