Antenatal umbilical coiling index in gestational diabetes mellitus and non-gestational diabetes pregnancy

摘要

ObjectiveUmbilical cord abnormalities increase fetal morbidity and mortality. This study was designed to compare antenatal umbilical coiling index (aUCI) in gestational diabetes mellitus (GDM) and non-gestational diabetes mellitus (non-GDM) pregnancy, considering uncertainties about the best time to perform antenatal ultrasonography scan. Materials and MethodsIn this prospective study, 246 parturients were included, 123 with GDM and 123 with non-GDM pregnancy. Gestational diabetes was confirmed at 24–28 weeks of gestation (WG) using one-step strategy. An anatomical ultrasound survey of placenta and umbilical cord was performed at 18–23 as well as 37–41 weeks of gestational age. ResultsAt 18–23 WG, the frequency distribution (10th, 90th percentiles, mean?±?SD) of the aUCI in the GDM and non-GDM groups were (0.13,0.66,0.32?±?0.19) and (0.18,0.74, 0.4?±?0.31) respectively. These values were (0.12,0.4, 0.25?±?0.11) in the GDM group at 37–41 WG and (0.17,0.43, 0.29?±?0.11) in the non-GDM group. A significant relationship was detected between UCI value and GDM/non-GDM groups at both antenatal evaluations (18–23 WG; P?=?0.002, 37–41WG; P? 90th) (P?=?0.001). However, hypocoiling were significantly more frequent in GDM than non-GDM in both antenatal evaluations (P?