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Economic Conditions in Early Life and Circulatory Disease Mortality

机译:早期生命和循环疾病死亡率的经济状况

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I test the Developmental Origins of Health and Disease hypothesis using a cohort perspective on mortality. I combine data from the National Health Interview Survey Linked Mortality Files, 1986-2006, and U.S. economic data between 1902 and 1956 (403,746 respondents and 39,439 deaths), to estimate how exposures to adverse economic conditions in utero and during the first three years of life affect circulatory disease mortality risk in adulthood. I also examine cohort-based variation in these associations. Findings suggest that in utero exposures to poor economic conditions increased risk of death from circulatory diseases. Results are consistent with theory and evidence suggesting that developmental processes early in life are strongly associated with circulatory disease susceptibility in older adulthood. However, findings indicate that the mortality effects of these early-life exposures have likely weakened across birth cohorts.
机译:我使用队列的死亡率测试健康和疾病假设的发育起源。 我将数据与1986 - 2006年的国家健康面试调查相关的数据,1986 - 2006年和1902年至1956年间的美国经济数据(403,746名受访者和39,439人死亡)结合起来,以估算UTERO和前三年的不利经济状况的曝光方式。 生活会影响成年期的循环疾病死亡率风险。 我还研究了这些关联的基于队列的变体。 结果表明,在子宫暴露于贫困的经济条件下,循环疾病的死亡风险增加。 结果与理论和证据一致,表明在年龄较老年的成年期疾病易感性与循环疾病易感性有关。 然而,调查结果表明,这些早期暴露的死亡率效应可能在出生队列中减弱。

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