Short‐term neurological outcomes in ischemic and hemorrhagic pediatric stroke

摘要

Abstract Background The aim of this study was to retrospectively assess short‐term neurological outcomes in pediatric stroke with regard to patient characteristics. Methods Children aged 28 days–18 years with arterial ischemic stroke ( AIS ), cerebral sinovenous thrombosis ( CSVT ), and hemorrhagic stroke ( HS ) between 2007 and 2013 were evaluated. Neurological findings in the first 3 months were accepted as short‐term prognosis, and modified Rankin scale was used. Results A total of 33 patients (62%) with AIS , 12 (23%) with HS , and eight (15%) with CSVT were included. Moya moya syndrome was the most common new diagnosis in AIS . Stroke recurred in five (15%); and one AIS patient with posterior circulation infarct died (3%). Prognosis in AIS was favorable for 20 patients (61%) and poor for 13 patients (39%). Forty‐two percent of HS were of vascular origin. Seven patients (70%) with HS had good prognosis and three (30%) had poor prognosis with no death. Homocysteine‐related hypercoagulability was most frequently noted in the etiology of CSVT . Synchronous systemic thrombosis was observed in three CSVT patients (37.5%) and death occurred in two (25%). Prognosis was evaluated as favorable for three CSVT patients (37.5%) and poor for five (62.5%). For thrombophilia, thrombosis panel was performed fully in 83% of AIS and CSVT patients. Conclusions Pediatric stroke is associated with a poor prognosis in a substantial number of patients in the short term, with CSVT having the worst prognosis. Detailed patient characteristics are listed not only for ischemic but also for hemorrhagic stroke; and a full thrombosis panel was achieved for most ischemic stroke patients.