MECHANISMS OF ACTION OF CFTR CORRECTOR ON RESCUING F508DEL-CFTR IN STEM CELLS-DERIVED INTESTINAL MODELS USING CLICK CHEMISTRY

Arora Kavisha; Zhang Weiqiang; Actis Marcello; Fujii Naoaki; Li Chunying; Frizzell Raymond A.; Naren A. P.

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MECHANISMS OF ACTION OF CFTR CORRECTOR ON RESCUING F508DEL-CFTR IN STEM CELLS-DERIVED INTESTINAL MODELS USING CLICK CHEMISTRY

机译：CFTR校正器在使用点击化学中拯救干细胞衍生肠道模型中的F508DEL-CFTR的作用机制

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来源
《Pediatric Pulmonology》 |2016年第45期|共2页
作者
Arora Kavisha; Zhang Weiqiang; Actis Marcello; Fujii Naoaki; Li Chunying; Frizzell Raymond A.; Naren A. P.;
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作者单位

Cincinnati Childrens Pediat Cincinnati OH USA;

Univ Tennessee Ctr Hlth Sci Pediat Memphis TN 38163 USA;

St Jude Childrens Res Hosp Dept Chem Biol &

Therapeut 332 N Lauderdale St Memphis TN 38105 USA;

St Jude Childrens Res Hosp Dept Chem Biol &

Therapeut 332 N Lauderdale St Memphis TN 38105 USA;

Wayne State Univ Biochem &

Mol Biol Detroit MI USA;

Univ Pittsburgh Sch Med Dept Cell Biol Pittsburgh PA USA;

Cincinnati Childrens Pediat Cincinnati OH USA;

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正文语种 eng
中图分类儿科学;
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1. MECHANISMS OF ACTION OF CFTR CORRECTOR ON RESCUING F508DEL-CFTR IN STEM CELLS-DERIVED INTESTINAL MODELS USING CLICK CHEMISTRY [J] . Arora Kavisha, Zhang Weiqiang, Actis Marcello, Pediatric Pulmonology . 2016,第Suppla51期

机译：CFTR纠正剂通过点击化学作用恢复干细胞肠道模型中F508DEL-CFTR的作用机理
2. INVOLVEMENT OF EDEM1 AND EDEM2 IN F508DEL-CFTR TRAFFICKING DEFECT AND IDENTIFICATION OF A NEW SERIES OF CORRECTORS WITH AN EDEM-DEPENDENT MECHANISM OF ACTION [J] . Sidelarbi K., Bertrand J., Becq F., Pediatric Pulmonology . 2016,第Suppla51期

机译：EDEM1和EDEM2参与F508DEL-CFTR交易缺陷和新系列的依赖于EDEM的作用机理的鉴定
3. INVOLVEMENT OF EDEM1 AND EDEM2 IN F508DEL-CFTR TRAFFICKING DEFECT AND IDENTIFICATION OF A NEW SERIES OF CORRECTORS WITH AN EDEM-DEPENDENT MECHANISM OF ACTION [J] . Sidelarbi K., Bertrand J., Becq F., Pediatric Pulmonology . 2016,第Suppla45期

机译：在F508DEL-CFTR运输缺陷和识别新系列校正器中的EDEM1和EDEM2参与具有EDEM依赖的行动机制
4. Turbulence-Chemistry Interaction in a Co-axial Methane Diffusion Flame: Comparison of Reaction Mechanisms and Combustion Models [C] . A. Karimi, M. Rajagopal, M. R. Nalim Technical Meeting of the Central States Section of the Combustion Institute . 2012

机译：湍流 - 化学相互作用在共轴甲烷扩散火焰中：反应机制和燃烧模型的比较
5. Development of antimicrobial agent with novel mechanisms of actions, and, 1,2,4,5-tetrazine click chemistry and its application in DNA postsynthetic functionalization. [D] . Chen, Weixuan. 2012

机译：具有新型作用机理的抗菌剂的开发以及1,2,4,5-四嗪点击化学及其在DNA合成后功能中的应用。
6. Partial Rescue of F508del-CFTR Stability and Trafficking Defects by Double Corrector Treatment [O] . Valeria Capurro, Valeria Tomati, Elvira Sondo, 2021

机译：双校正器治疗部分救援F508DEL-CFTR稳定性和贩运缺陷
7. Revertants, Low Temperature, and Correctors Reveal the Mechanism of F508del-CFTR Rescue by VX-809 and Suggest Multiple Agents for Full Correction [O] . Farinha Carlos M., King-Underwood John, Sousa Marisa, 2013

机译：还原剂，低温和校正剂揭示了VX-809拯救F508del-CFTR的机理，并建议使用多种试剂进行全面校正

MECHANISMS OF ACTION OF CFTR CORRECTOR ON RESCUING F508DEL-CFTR IN STEM CELLS-DERIVED INTESTINAL MODELS USING CLICK CHEMISTRY

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