Immunohistochemical Antibody Panel for the Differential Diagnosis of Pancreatic Ductal Carcinoma From Gastrointestinal Contamination and Benign Pancreatic Duct Epithelium in Endoscopic Ultrasound-Guided Fine-Needle Aspiration

Furuhata Ayako; Minamiguchi Sachiko; Shirahase Hiroyuki; Kodama Yuzo; Adachi Souichi; Sakurai Takaki; Haga Hironori

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Immunohistochemical Antibody Panel for the Differential Diagnosis of Pancreatic Ductal Carcinoma From Gastrointestinal Contamination and Benign Pancreatic Duct Epithelium in Endoscopic Ultrasound-Guided Fine-Needle Aspiration

机译：免疫组织化学抗体面板对于胃肠道污染和良性胰管上皮的肠道癌肠道癌患者在内窥镜超声波引导的细针穿刺中的肠道污染和良性胰管上皮

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Objectives: The diagnosis of pancreatic ductal adenocarcinoma (PDAC) by endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) can be challenging to distinguish tumor cells from benign epithelium (BE). The aim of the present study was to set a minimal antibody panel to differentiate PDAC from contaminated BE in EUS-FNA specimens.

机译：目的：通过内窥镜超声引导的细针抽吸（EUS-FNA）诊断胰腺导管腺癌（PDAC）可能具有挑战性，以区分肿瘤细胞来自良性上皮（是）。本研究的目的是设定最小抗体面板，以区分PDAC污染在EUS-FNA标本中。

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来源
《Pancreas》 |2017年第4期|共8页
作者
Furuhata Ayako; Minamiguchi Sachiko; Shirahase Hiroyuki; Kodama Yuzo; Adachi Souichi; Sakurai Takaki; Haga Hironori;
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作者单位

Kyoto Univ Grad Sch Med Dept Diagnost Pathol Kyoto Japan;

Kyoto Univ Grad Sch Med Dept Diagnost Pathol Kyoto Japan;

Kyoto Univ Grad Sch Med Dept Diagnost Pathol Kyoto Japan;

Kyoto Univ Grad Sch Med Dept Gastroenterol &

Hepatol Kyoto Japan;

Kyoto Univ Grad Sch Med Human Hlth Sci Kyoto Japan;

Kyoto Univ Grad Sch Med Dept Diagnost Pathol Kyoto Japan;

Kyoto Univ Grad Sch Med Dept Diagnost Pathol Kyoto Japan;

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原文格式 PDF
正文语种 eng
中图分类消化系及腹部疾病;
关键词
endoscopic ultrasound-guided fine-needle aspiration; tissue microarray; immunohistochemical panel; cell block;

机译：内窥镜超声引导的细针吸入;组织微阵列;免疫组化板;细胞块;

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专利

1. Immunohistochemical Antibody Panel for the Differential Diagnosis of Pancreatic Ductal Carcinoma From Gastrointestinal Contamination and Benign Pancreatic Duct Epithelium in Endoscopic Ultrasound-Guided Fine-Needle Aspiration [J] . Furuhata Ayako, Minamiguchi Sachiko, Shirahase Hiroyuki, Pancreas . 2017,第4期

机译：免疫组织化学抗体面板对于胃肠道污染和良性胰管上皮的肠道癌肠道癌患者在内窥镜超声波引导的细针穿刺中的肠道污染和良性胰管上皮
2. Analysis of BRCAness with multiplex ligation-dependent probe amplification using formalin-fixed and paraffin-embedded pancreatic ductal adenocarcinoma tissue obtained via endoscopic ultrasound-guided fine-needle aspiration biopsy [J] . Okuwaki Kosuke, Masutani Hironori, Imaizumi Hiroshi, Pancreatology: official journal of the International Association of Pancreatology (IAP) ... [et al.] . 2019,第3期

机译：通过内窥镜超声引导细针穿刺活检获得多重固定和石蜡嵌入胰腺导管腺癌组织的多重连接依赖性探针扩增的BRCaness分析
3. Branch Duct Intraductal Papillary Mucinous Neoplasms of the Pancreas Involving Type 1 Localized Autoimmune Pancreatitis with Normal Serum IgG4 Levels Successfully Diagnosed by Endoscopic Ultrasound-guided Fine-needle Aspiration and Treated without Pancreatic Surgery [J] . Shinsuke Koshita, Yutaka Noda, Kei Ito, Internal medicine. . 2017,第10期

机译：内镜超声引导下细针穿刺成功诊断胰腺伴1型局部自身免疫性胰腺炎的胰管导管乳头状黏液性肿瘤，血清IgG4水平正常，未经胰腺手术治疗
4. The integration of single fiber reflectance (SFR) spectroscopy during endoscopic ultrasound-guided fine needle aspirations (EUS-FNA) in pancreatic masses: a feasibility study [C] . Paulien L. Stegehuis, Leonora S. F. Boogerd, Akin Inderson, Endoscopic microscopy XI; and Optical Techniques in Pulmonary Medicine III . 2016

机译：内镜超声引导下胰腺穿刺细针穿刺术（EUS-FNA）中单纤维反射率（SFR）光谱的集成：可行性研究
5. MMP-7 modulates the transition of normal pancreatic acinar cells to metaplastic ducts associated with the neoplastic epithelium of pancreatic ductal adenocarcinoma [D] . Johnson, Johnny 2007

机译：MMP-7调节正常胰腺腺泡细胞向与胰腺导管腺癌的肿瘤上皮相关的化生导管的过渡
6. Branch Duct Intraductal Papillary Mucinous Neoplasms of the Pancreas Involving Type 1 Localized Autoimmune Pancreatitis with Normal Serum IgG4 Levels Successfully Diagnosed by Endoscopic Ultrasound-guided Fine-needle Aspiration and Treated without Pancreatic Surgery [O] . Shinsuke Koshita, Yutaka Noda, Kei Ito, 2017

机译：内镜超声引导下细针穿刺成功诊断胰腺伴1型局部自身免疫性胰腺炎的胰管导管乳头状黏液性肿瘤血清IgG4水平正常未经胰腺手术治疗
7. Characterization and Differential Diagnosis of Cystic Pancreatic Lesions: An Emphasis on Endoscopic Ultrasound-Guided Fine-Needle Aspiration [O] . Yoon WJ, Brugge WR 2013

机译：囊性胰腺病变的特征与鉴别诊断：以内镜超声引导下的细针抽吸为重点

Immunohistochemical Antibody Panel for the Differential Diagnosis of Pancreatic Ductal Carcinoma From Gastrointestinal Contamination and Benign Pancreatic Duct Epithelium in Endoscopic Ultrasound-Guided Fine-Needle Aspiration

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