Safety and efficacy of re-treatments with pyronaridine-artesunate in African patients with malaria: a substudy of the WANECAM randomised trial

Sagara Issaka; Beavogui Abdoul Habib; Zongo Issaka; Soulama Issiaka; Borghini-Fuhrer Isabelle; Fofana Bakary; Camara Daouda; Some Anyirekun F.; Coulibaly Aboubacar S.; Traore Oumar B.; Dara Niawanlou; Kabore Moise J. T.; Thera Ismaila; Compaore Yves D.; Sylla Malick Minkael; Nikiema Frederic; Diallo Mamadou Saliou; Dicko Alassane; Gil Jose Pedro; Borrmann Steffen; Duparc Stephan; Miller Robert M.; Doumbo Ogobara K.; Shin Jangsik; Bjorkman Anders; Ouedraogo Jean-Bosco; Sirima Sodiomon B.; Djimde Abdoulaye A.

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Safety and efficacy of re-treatments with pyronaridine-artesunate in African patients with malaria: a substudy of the WANECAM randomised trial

机译：在非洲疟疾患者中重新治疗的安全性和疗效 - 疟疾患者：血糖随机试验的替换

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Background Sparse data on the safety of pyronaridine-artesunate after repeated treatment of malaria episodes restrict its clinical use. We therefore compared the safety of pyronaridine-artesunate after treatment of the first episode of malaria versus re-treatment in a substudy analysis.

机译：背景技术对疟疾事件重复治疗后Pyronaridine-artesunate的安全性的稀疏数据限制了其临床应用。因此，我们将在替换分析中治疗疟疾与重新治疗的第一发作后，比较了Pyronaridine-artesunate的安全性。

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《SIAM journal on applied dynamical systems》 |2017年第2期|共10页
作者
Sagara Issaka; Beavogui Abdoul Habib; Zongo Issaka; Soulama Issiaka; Borghini-Fuhrer Isabelle; Fofana Bakary; Camara Daouda; Some Anyirekun F.; Coulibaly Aboubacar S.; Traore Oumar B.; Dara Niawanlou; Kabore Moise J. T.; Thera Ismaila; Compaore Yves D.; Sylla Malick Minkael; Nikiema Frederic; Diallo Mamadou Saliou; Dicko Alassane; Gil Jose Pedro; Borrmann Steffen; Duparc Stephan; Miller Robert M.; Doumbo Ogobara K.; Shin Jangsik; Bjorkman Anders; Ouedraogo Jean-Bosco; Sirima Sodiomon B.; Djimde Abdoulaye A.;
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作者单位

Univ Sci Tech &

Technol Bamako Fac Pharm Dept Epidemiol Parasit Dis Malaria Res &

Training Ctr Bamako Mali;

Ctr Format &

Rech Sante Rurale Maferinyah Conakry Guinea;

Inst Rech Sci Sante Bobo Dioulasso Burkina Faso;

Natl Ctr Res &

Training Malaria Ouagadougou Burkina Faso;

Med Malaria Venture Geneva Switzerland;

Univ Sci Tech &

Technol Bamako Fac Pharm Dept Epidemiol Parasit Dis Malaria Res &

Training Ctr Bamako Mali;

Ctr Format &

Rech Sante Rurale Maferinyah Conakry Guinea;

Natl Ctr Res &

Training Malaria Ouagadougou Burkina Faso;

Univ Sci Tech &

Technol Bamako Fac Pharm Dept Epidemiol Parasit Dis Malaria Res &

Training Ctr Bamako Mali;

Univ Sci Tech &

Technol Bamako Fac Pharm Dept Epidemiol Parasit Dis Malaria Res &

Training Ctr Bamako Mali;

Natl Ctr Res &

Training Malaria Ouagadougou Burkina Faso;

Univ Sci Tech &

Technol Bamako Fac Pharm Dept Epidemiol Parasit Dis Malaria Res &

Training Ctr Bamako Mali;

Inst Rech Sci Sante Bobo Dioulasso Burkina Faso;

Ctr Format &

Rech Sante Rurale Maferinyah Conakry Guinea;

Inst Rech Sci Sante Bobo Dioulasso Burkina Faso;

Ctr Format &

Rech Sante Rurale Maferinyah Conakry Guinea;

Univ Sci Tech &

Technol Bamako Fac Pharm Dept Epidemiol Parasit Dis Malaria Res &

Training Ctr Bamako Mali;

Karolinska Inst Karolinska Univ Hosp Dept Physiol &

Pharmacol Stockholm Sweden;

Univ Tubingen Inst Trop Med Tubingen Germany;

Med Malaria Venture Geneva Switzerland;

Apt Solut Stevenage Herts England;

Univ Sci Tech &

Technol Bamako Fac Pharm Dept Epidemiol Parasit Dis Malaria Res &

Training Ctr Bamako Mali;

Shin Poong Pharmaceut Co Seoul South Korea;

Karolinska Inst Dept Microbiol Tumor &

Cell Biol Stockholm Sweden;

Inst Rech Sci Sante Bobo Dioulasso Burkina Faso;

Natl Ctr Res &

Training Malaria Ouagadougou Burkina Faso;

Univ Sci Tech &

Technol Bamako Fac Pharm Dept Epidemiol Parasit Dis Malaria Res &

Training Ctr Bamako Mali;

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正文语种 eng
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专利

1. Safety and efficacy of re-treatments with pyronaridine-artesunate in African patients with malaria: a substudy of the WANECAM randomised trial [J] . Sagara Issaka, Beavogui Abdoul Habib, Zongo Issaka, SIAM journal on applied dynamical systems . 2017,第2期

机译：在非洲疟疾患者中重新治疗的安全性和疗效 - 疟疾患者：血糖随机试验的替换
2. Efficacy and safety of a fixed-dose oral combination of pyronaridine-artesunate compared with artemether-lumefantrine in children and adults with uncomplicated Plasmodium falciparum malaria: a randomised non-inferiority trial [J] . Antoinette KTshefu Oumar Gaye Kassoum Kayentao Ricardo Thompson Kirana M Bhatt Sanie S S Sesay Dorina G Bustos Emiliana Tjitra George Bedu Addo Isabelle Borgbmi Fuhrer Stephan Duparc Chang Sik Shin Lawrence Fleckenstein The Lancet . 2010,第9724期

机译：固定剂量口服吡咯烷-青蒿琥酯与蒿甲醚-氟美汀相比在单纯性恶性疟原虫疟疾儿童和成人中的疗效和安全性：一项非劣效随机性试验
3. Safety and efficacy of pyronaridine-artesunate in uncomplicated acute malaria: an integrated analysis of individual patient data from six randomized clinical trials [J] . Stephan Duparc, Isabelle Borghini-Fuhrer, Carl J Craft, Malaria Journal . 2013,第1期

机译：Pyronaridine-artesunate在简单的急性疟疾中的安全性和有效性：来自六种随机临床试验的个体患者数据的综合分析
4. The best evidence: A randomised controlled trial to assess the efficacy of a nutraceutical to treat headshaking [C] . Gina L. Pinchbeck British Equine Veterinary Association Congress . 2009

机译：最好的证据：随机对照试验，以评估营养保健治疗耳机的功效
5. Efficacy and safety of novel collagen conduits filled with collagen filaments to treat patients with peripheral nerve injury: A multicenter, controlled, open-label clinical trial [D] . Saeki Masaomi, 佐伯将臣 2019

机译：充满胶原细丝的新型胶原蛋白导管治疗周围神经损伤患者的疗效和安全性：一项多中心，对照，开放标签的临床试验
6. Safety and efficacy of re-treatments with pyronaridine-artesunate in African patients with malaria: a substudy of the WANECAM randomised trial [O] . Issaka Sagara, Abdoul Habib Beavogui, Issaka Zongo, -1

机译：WANECAM随机试验亚研究在非洲疟疾患者中用吡咯烷-青蒿琥酯复治的安全性和有效性
7. Safety and efficacy of re-treatments with pyronaridine-artesunate in African patients with malaria: a substudy of the WANECAM randomised trial [O] . Sagara Issaka, Beavogui Abdoul Habib, Zongo Issaka, 2016

机译：WANECAM随机试验的亚研究：吡咯烷-青蒿琥酯复治在非洲疟疾患者中的安全性和有效性

Safety and efficacy of re-treatments with pyronaridine-artesunate in African patients with malaria: a substudy of the WANECAM randomised trial

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