A Carbothioamide-Based Chemosensor for Zinc Based on Ratiometric Fluorescence in Aqueous Media

摘要

A new carbothioamide-based ratiometric fluorescent chemosensor ITC-M ((E)-N-benzhydryl-2-(2-hydroxy-3-methoxybenzylidene) hydrazine-1-carbothioamide) was devised and synthesized. Sensor ITC-M could detect zinc ion in aqueous media which exhibited a significant fluorescence color change from green to blue. The detection limit (0.53 μM) of ITC-M for Zn~(2+) was far lower than the guideline of World Health Organization in drinking water. In addition, ITC-M is reusable by using ethylenediaminetetraacetic acid (EDTA).