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Towards prevention of post-traumatic osteoarthritis: report from an international expert working group on considerations for the design and conduct of interventional studies following acute knee injury

机译:在预防创伤后骨关节炎:从急性膝关节损伤后的介入研究设计和进行的国际专家工作组报告

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摘要

Objective: There are few guidelines for clinical trials of interventions for prevention of post-traumatic osteoarthritis (PTOA), reflecting challenges in this area. An international multi-disciplinary expert group including patients was convened to generate points to consider for the design and conduct of interventional studies following acute knee injury.
机译:目的:临床试验临床试验较少预防创伤后骨关节炎(PTOA),反映了该地区的挑战。 在包括患者包括患者的国际多学科专家组,以便在急性膝关节损伤后进行介入研究的设计和进行。

著录项

  • 来源
    《Osteoarthritis and cartilage》 |2019年第1期|共11页
  • 作者单位

    Univ Oxford Arthrit Res UK Ctr Osteoarthrit Pathogenesis Nuffield Dept Orthopaed Rheumatol &

    Keele Univ Inst Primary Care &

    Hlth Sci Arthrit Res UK Primary Care Ctr Keele Staffs England;

    Univ Leeds Leeds Inst Rheumat &

    Musculoskeletal Med Leeds W Yorkshire England;

    Lund Univ Dept Clin Sci Lund Fac Med Orthopaed Lund Sweden;

    Lund Univ Dept Clin Sci Lund Fac Med Orthopaed Lund Sweden;

    Boston Univ Sch Med Clin Epidemiol Res &

    Training Unit Boston MA 02118 USA;

    Abbvie Biores Ctr Immunol Dev Worcester MA USA;

    Univ Calif San Francisco Dept Radiol &

    Biomed Imaging Musculoskeletal Quantitat Imaging Res Grp;

    Univ Hlth Board Dept Trauma &

    Orthopaed Cardiff S Glam Wales;

    Univ Oxford Nuffield Dept Orthopaed Rheumatol &

    Musculokeleta SITU Oxford England;

    Lund Univ Dept Clin Sci Lund Fac Med Orthopaed Lund Sweden;

    Duke Univ Sch Med Duke Mol Physiol Inst Durham NC 27706 USA;

    Univ Erlangen Nurnberg Dept Radiol Erlangen Germany;

    Univ Leeds Leeds Inst Rheumat &

    Musculoskeletal Med Leeds W Yorkshire England;

    Cardiff Univ Sch Biosci Arthrit Res UK Biomech &

    Bioengn Ctr Cardiff S Glam Wales;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 骨科学(运动系疾病、矫形外科学);
  • 关键词

    Osteoarthritis; Injury; Outcome; Clinical trial; Knee; Considerations;

    机译:骨关节炎;伤害;结果;临床试验;膝盖;考虑因素;

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