Preparation of Aerogel Materials Based on Alginate-Chitosan Interpolymer Complex Using Supercritical Fluids

摘要

Aerogel materials based on the interpolymer complex of alginate with chitosan using supercritical fluids technology were obtained. It was established that obtained aerogels have a developed mesoporous structure and a specific surface area of up to 243 m2/g. The average pore size equals 14.8 nm. The possibility of using the aerogels with the inclusion of antibiotic levomycetin as a basis for creating wound dressings was shown. It was estimated that slow release of the drug (70% during 5 h) from the aerogel matrix provides prolonged and safe supply of the drug to the surface of a wound.