Addressing the Role of Obesity in Endometrial Cancer Risk, Prevention, and Treatment

摘要

The worldwide obesity epidemic has had a major impact on the health and well-being of both men and women. Obesity is well established as a major causal factor for the development of cardiovascular disease, diabetes, a number of cancers, and several other diseases. There is a strong association between obesity and endometrial cancer among both premenopausal and postmenopausal women. This association follows a dose-response relationship: the incidence of endometrial cancer increases as body mass index increases. With the increasing rates of obesity in recent decades, the incidence of endometrial cancer is expected to rise.