The normal tissue complication probability model-based approach considering uncertainties for the selective use of radiation modality in primary liver cancer patients

摘要

Purpose: To predict the probability of radiation-induced liver toxicity (RILT) and implement the normal tissue complication probability (NTCP) model-based approach considering confidence intervals (CIs) to select patients for new treatment techniques, such as proton beam therapy, based on a certain NTCP reduction (Delta NTCP) threshold for primary liver cancer patients.