SBRT combined with concurrent chemoradiation in stage III NSCLC: Feasibility study of the phase I Hybrid trial

Peulen Heike; Franssen Gijs; Belderbos Jose; van der Bijl Erik; Tijhuis Angela; Rossi Maddalena; Sonke Jan-Jakob; Damen Eugene

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SBRT combined with concurrent chemoradiation in stage III NSCLC: Feasibility study of the phase I Hybrid trial

机译：SBRT结合阶段III NSCLC中的同时校长：I阶段杂交试验的可行性研究

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Purpose: To assess the technical and clinical feasibility of the phase I Hybrid trial (NCT01933568), combining SBRT of the primary tumor (PT) and fractionated radiotherapy (FRT) to the lymph nodes (LN).

机译：目的：评估I型杂种试验（NCT01933568）的技术和临床可行性，将原发性肿瘤（Pt）和分级放射疗法（FRT）的SBRT与淋巴结（LN）组合。

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来源
《Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology》 |2020年第1期|共6页
作者
Peulen Heike; Franssen Gijs; Belderbos Jose; van der Bijl Erik; Tijhuis Angela; Rossi Maddalena; Sonke Jan-Jakob; Damen Eugene;
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作者单位

Netherlands Canc Inst Dept Radiat Oncol Postbox 90203 NL-1006 BE Amsterdam Netherlands;

Netherlands Canc Inst Dept Radiat Oncol Postbox 90203 NL-1006 BE Amsterdam Netherlands;

Netherlands Canc Inst Dept Radiat Oncol Postbox 90203 NL-1006 BE Amsterdam Netherlands;

Netherlands Canc Inst Dept Radiat Oncol Postbox 90203 NL-1006 BE Amsterdam Netherlands;

Netherlands Canc Inst Dept Radiat Oncol Postbox 90203 NL-1006 BE Amsterdam Netherlands;

Netherlands Canc Inst Dept Radiat Oncol Postbox 90203 NL-1006 BE Amsterdam Netherlands;

Netherlands Canc Inst Dept Radiat Oncol Postbox 90203 NL-1006 BE Amsterdam Netherlands;

Netherlands Canc Inst Dept Radiat Oncol Postbox 90203 NL-1006 BE Amsterdam Netherlands;

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原文格式 PDF
正文语种 eng
中图分类肿瘤学;
关键词
SBRT; Concurrent chemoradiotherapy; Locally advanced NSCLC;

机译：SBRT;同时进行化学疗法;当地高级NSCLC;

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专利

1. SBRT combined with concurrent chemoradiation in stage III NSCLC: Feasibility study of the phase I Hybrid trial [J] . Peulen Heike, Franssen Gijs, Belderbos Jose, Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology . 2020,第1期

机译：SBRT结合阶段III NSCLC中的同时校长：I阶段杂交试验的可行性研究
2. The SABRTooth feasibility trial protocol: a study to determine the feasibility and acceptability of conducting a phase III randomised controlled trial comparing stereotactic ablative radiotherapy (SABR) with surgery in patients with peripheral stage I non-small cell lung cancer (NSCLC) considered to be at higher risk of complications from surgical resection [J] . M. P. Snee, L. McParland, F. Collinson, Pilot and Feasibility Studies . 2016,第1期

机译：SABRTooth可行性试验方案：一项研究，用于确定在III期非小细胞肺癌（NSCLC）患者中进行立体定向消融放疗（SABR）与手术比较的III期随机对照试验的可行性和可接受性手术切除引起并发症的风险更高
3. Continuous Intravenous Pumping of Recombinant Human Endostatin Combined With Concurrent Chemoradiation Therapy in Patients With Unresectable Stage III Non-Small Cell Lung Cancer: Preliminary Data of a Prospective Multicenter Phase 1/2 Clinical Trial (NCT01733589) [J] . Hui Z., Ma H., Wu R., International Journal of Radiation Oncology, Biology, Physics . 2014,第5Suppla期

机译：不可切除的III期非小细胞肺癌患者持续静脉注射重组人内皮抑素并同时进行化学放疗：一项预期的多中心1/2期临床试验的初步数据（NCT01733589）
4. Radiomic Features Predict Local Failure-free Survival in Stage Ⅲ NSCLC Adenocarcinoma Treated with Chemoradiation [C] . Jose Marcio Luna, Andrew R. Barsky, Russell T. Shinohara, Conference on Medical Imaging: Computer-Aided Diagnosis . 2021

机译：辐射瘤特征预测Ⅲ期NSCLC腺癌中的局部失效存活率
5. The effectiveness of chemoradiation for stage III non-small-cell lung cancer patients at the Kingston Regional Cancer Center (Ontario). [D] . Sinclair, Suzanne Marie. 2003

机译：金斯敦地区癌症中心（安大略省）对III期非小细胞肺癌患者进行化学放射治疗的有效性。
6. The SABRTooth feasibility trial protocol: a study to determine the feasibility and acceptability of conducting a phase III randomised controlled trial comparing stereotactic ablative radiotherapy (SABR) with surgery in patients with peripheral stage I non-small cell lung cancer (NSCLC) considered to be at higher risk of complications from surgical resection [O] . M. P. Snee, L. McParland, F. Collinson, 2016

机译：SABRTooth可行性试验方案：一项研究用于确定在III期非小细胞肺癌（NSCLC）患者中进行立体定向消融放疗（SABR）与手术比较的III期随机对照试验的可行性和可接受性手术切除并发症的风险更高
7. PV-0277: SBRT with concurrent chemoradiation in stage III NSCLC: first results of the phase I Hybrid trial [O] . Peulen H., Sonke J.J., Van der Bijl E., 2016

机译：PV-0277：SBRT与III期NSCLC同时进行化学放射治疗：I期杂交试验的初步结果

SBRT combined with concurrent chemoradiation in stage III NSCLC: Feasibility study of the phase I Hybrid trial

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