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Effect of structural hybrid design on mechanical and biological properties of CoCr scaffolds fabricated by selective laser melting

机译:结构杂交设计对选择性激光熔化制造的CoCr型支架机械和生物学性能的影响

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Purpose - The purpose of this study was to bring a new structural hybrid design approach to improve the mechanical and biological properties of the bone scaffolds fabricated by laser powder bed fusion, selective laser melting (SLM). Design/methodology/approach - In designing the hybrid scaffolds, different unit cells were used such as dodecahedron (DCH), grid (G), octet-truss (OCT) with partially dense (PDsl) and fully dense (FDsl) surface layers. After fabrication of scaffolds on SLM machine, compression test and cell viability test were applied to observe the effect of hybrid design on mechanical and biological properties of the scaffolds. Findings - It has been observed that designing the scaffold with partially dense or FDsl surfaces did not have a critical effect on the cell viability. On the contrary, the compression strength of scaffold increased from 56 to 100 MPa when the surface layer of the scaffold was designed as FDsl surface instead of partially dense surface. It has also been observed that the scaffold having the highest hybridity (PDsl+G+DCH+OCT) delivered the highest cell viability performance and had a compressive strength slightly higher than that of the scaffolds with single unit cell, PDsl+OCT. Originality/value - This study brings a new approach to designing femur bone scaffold for fabricating with SLM. This hybrid design approach, including different unit cells in a single scaffold, covers many requirements of femur bone in terms of mechanical and biological properties.
机译:目的 - 本研究的目的是提高一种新的结构混合动力设计方法来改善激光粉末融合,选择性激光熔化(SLM)制造的骨支架的机械和生物学特性。设计/方法/方法 - 在设计混合支架时,使用不同的单位细胞,例如十二烷二酮(DCH),曲格(G),八位字节桁架(OCT),具有部分致密(PDSL)和完全致密(FDSL)表面层。在SLM机器上制造支架后,施用压缩试验和细胞活力测试以观察混合式设计对支架的机械和生物学性质的影响。发现 - 已经观察到,使用部分致密的或FDSL表面设计支架对细胞活力没有临界影响。相反,当支架的表面层设计为FDS1表面而不是部分致密的表面时,支架的压缩强度从56到100MPa增加到100MPa。还观察到具有最高杂交(Pds1 + G + DCH + OCT)的支架递送了最高的细胞活力性能,并且具有略高于具有单个单元电池的支架PDSL + OCT的压缩强度略高。原创性/价值 - 本研究为设计股骨骨架以纺织用SLM制造的新方法。这种混合设计方法包括单个支架中的不同单元电池,涵盖了机械和生物学性质方面的股骨骨骼的许多要求。

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