Current Progress in Synthesis, Characterization and Applications of Silver Nanoparticles: Precepts and Prospects

摘要

Background: Silver nanoparticles (AgNPs), are amongst the utmost striking nanosizedmaterials that are extensively applied in a variety of biomedical applications whichincludes diagnostic use, disease management, medical device coating, drug delivery and forpersonal health care.Discussion: With the growing interest and its application in the health care sector, it is becomingnecessary for a better understanding and exploration of AgNPs mechanism of actionlike biological interaction, their possible toxicity, and safety concern to human exposure.AgNPs have been the subject of researchers attention and interest due to the uniqueproperties and quality such as shape and size depending optical, electrical, and antimicrobialpotentials (antibacterial, antifungal, antiviral etc.). In recent times, several studies havebeen conducted on AgNPs antimicrobial potential and also a number of patents related to itssynthesis, clinical role and importance have also been registered. In this review, a shortoverview of AgNPs synthesis approach is presented (physical, chemical, and biological orgreen synthesis) and it also delivers a historical outlook of AgNPs application as an antimicrobialagent which includes combined evidence of microbial resistance and safety issueswith human exposure.