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Special Issue of Aerosol Science and Technology for Particulate Matter:Atmospheric Sciences,Exposure,and the Fourth Colloquium on PM and Human Health

机译:涉及颗粒物的气溶胶科学与技术特刊:大气科学,接触和第四次PM和人体健康专题讨论会

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In response to epidemiological studies published over twenty years ago,at least three research communities have been intensively studying airborne particulate matter (PM).These efforts have been coordinated by approaching the source-atmospheric accumulation/receptor-exposure-dose-health effects paradigm (adopted from NRC 2001) from different perspectives or along different parts of the paradigm.The atmospheric sciences communities consider the emissions of particles and precursors from sources,their transport and transformation in air to receptor locations,and finally removal from the atmosphere.The exposure communities' interest is to examine the pathways by which pollution or particulate matter,in this case,approaches and enters the body,typically by trying to relate PM concentrations at central location(s) to exposure and perhaps dose.Both the atmospheric sciences and exposure communities approach the paradigm from left to right.In contrast,the health effects communities have studied health outcomes,including hospital admissions,school absences,disease rates and deaths in human populations,and potential mechanisms of biological actions in laboratory settings.In general,the health effects communities approach the paradigm from right to left,attempting to correlate an observed adverse health effect with dose or exposure measures.For the most part,research results are reported in scientific publications and conferences for each community.Over the years there has been little effort to integrate information from these diverse groups in a substantive way.While a major attempt took place in 1998 at the Chapel Hill workshop (Albritton and Greenbaum 1998),little has occurred since.
机译:为了响应20年前发表的流行病学研究,至少三个研究社区一直在深入研究空气中的颗粒物(PM),这些努力通过接近源-大气累积/受体-暴露-剂量-健康效应范式进行了协调( (NRC 2001采纳)从不同角度或沿着范式的不同部分进行研究。大气科学界考虑了粒子和前体从源头的排放,它们在空气中的迁移和转化到受体位置,以及最后从大气中去除。我们的兴趣是研究在这种情况下污染或颗粒物进入并进入人体的途径,通常是通过尝试将中心位置的PM浓度与暴露量或剂量联系起来。大气科学和暴露社区从左到右接近范式。相反,对健康的影响研究社区d。健康结果,包括住院,入学,疾病发生率和人口死亡,以及实验室环境中生物行为的潜在机制。一般而言,健康影响社区从右到左接近范式,试图将观察到的不良反应与相关剂量或暴露量对健康的影响。在大多数情况下,研究结果在各个社区的科学出版物和会议中都有报道。多年来,人们一直在努力以实质性的方式整合来自这些不同群体的信息。该活动于1998年在教堂山工作室举行(Albritton and Greenbaum 1998),此后几乎没有发生过。

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