12-Hydroxycorniculatolide A from the Mangrove Tree, Lumnitzera littorea

摘要

A new macrocyclic lactone, 12-hydroxycorniculatolide A (1), along with three known compounds, comiculatolide A (2), 12-hydroxy-11-O-methyl-comiculatolide A (3) and 6,7-dimethoxycoumarin (4) were isolated from the methanolic extract of the twigs of Lumnitzera littorea. All compounds were characterized using spectroscopic methods. All compounds were screened against a panel of six Gram positive and five Gram negative bacteria.