机译:雷公藤内酯中断NLRP3炎性途径的双重作用,以衰减心肌纤维化
Third Mil Med Univ Army Med Univ Coll Pharm Dept Pharmacol Chongqing 400038 Peoples R China;
Third Mil Med Univ Army Med Univ Coll Pharm Dept Pharmacol Chongqing 400038 Peoples R China;
Third Mil Med Univ Army Med Univ Coll Pharm Dept Pharmacol Chongqing 400038 Peoples R China;
Third Mil Med Univ Army Med Univ Coll Pharm Dept Pharmacol Chongqing 400038 Peoples R China;
Third Mil Med Univ Army Med Univ Coll Pharm Dept Pharmacol Chongqing 400038 Peoples R China;
Third Mil Med Univ Army Med Univ Coll Pharm Dept Pharmacol Chongqing 400038 Peoples R China;
Third Mil Med Univ Army Med Univ Coll Pharm Dept Pharmacol Chongqing 400038 Peoples R China;
Third Mil Med Univ Army Med Univ Coll Pharm Dept Pharmacol Chongqing 400038 Peoples R China;
Third Mil Med Univ Army Med Univ Coll Pharm Dept Pharmacol Chongqing 400038 Peoples R China;
Third Mil Med Univ Army Med Univ Coll Pharm Dept Pharmacol Chongqing 400038 Peoples R China;
triptolide; cardiac fibrosis; inflammasome; NOD-like receptor protein 3; apoptosis-associated speck-like protein containing a CARD;
机译:雷公藤内酯中断NLRP3炎性途径的双重作用,以衰减心肌纤维化
机译:雷公藤内酯通过NLRP3炎症介导的MAPK / TGF-β1/ SMAD路径衰减心脏纤维化
机译:肉桂醛和别嘌呤醇通过减弱CD36介导的TLR4 / 6-IRAK4 / 1信号传导来抑制NLRP3炎性体激活,从而减少果糖诱导的心脏炎症和纤维化。
机译:基质金属蛋白酶和炎症途径在气道炎症和纤维化发育中的作用
机译:β-干扰素在柯萨奇病毒B3诱发的心肌炎中减轻心肌纤维化的作用。
机译:雷公藤甲素在中断NLRP3炎性体通路以减轻心脏纤维化中的双重作用
机译:通过抑制NF-κB途径来抑制NLRP3炎性的活化,提高心肌纤维化