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Surgical reconstruction is a cost-efficient treatment option for isolated PCL injuries

机译:手术重建是孤立的PCL伤害的成本效益的治疗选择

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Abstract Purpose and hypothesis The main purpose of the study is to put focus on the costs related to treating posterior cruciate ligament (PCL) injuries and the possible implications of chosen treatment strategy to the respective institutions and society. Methods Costs of treating PCL injuries nonoperatively and for both single-bundle (SB) and double-bundle (DB) reconstruction were estimated. These costs were translated into equivalent quality-adjusted life years (QALY) given a threshold value of Euro (?) 70,000 per QALY. Expected gain in knee osteoarthritis outcome score (KOOS) quality of life (QoL) following surgery based on KOOS data from 112 patients was used as a basis for calculating the cost efficiency ratio. Results The average calculated cost of nonoperative treatment was ?3382. Incremental cost for SB PCLR was ?8585 (154%) and another increment of ?5220 (61%) for DB PCLR using numbers from a European hospital. This is equivalent to increments of 0.074 (SB) and another 0.075 (DB) QALYs given the ?70,000 threshold. For DB to be as cost efficient as SB reconstruction, the incremental gain in KOOS QoL has to be at the same level as for SB reconstruction compared to nonoperative treatment. Conclusion Though surgical reconstruction adds a substantial cost to nonoperative treatment alone, it can be considered cost-effective. Double-bundle reconstruction is less cost efficient than SB reconstruction, but should probably still be considered the treatment of choice for certain patient categories. Randomized controlled trials looking at outcome following nonoperative, SB and DB PCL reconstruction are needed. The clinical relevance of this is that surgical reconstruction of PCL injuries is a cost-efficient treatment alternative in patients with an isolated PCL injury. This finding should be taken into consideration when deciding on how to treat these injuries. Level of evidence III.
机译:摘要目的和假设该研究的主要目的是重点关注与治疗后十字韧带(PCL)伤害的成本以及所选择的治疗战略对各自的机构和社会的可能影响。方法估计非手容处理PCL损伤的成本和单束(Sb)和双束(DB)重建。这些成本转化为等同的质量调整后的终身年(QALY)给出了每只QALY欧元(?)70,000的阈值。基于来自112名患者的KOOS数据的手术后,膝关节骨关节炎的预期增益(KOOS)寿命(QOL)用作计算成本效率比的基础。结果非手术治疗的平均计算成本是3382。 SB PCLR的增量费用是?8585(154%)和其他欧洲医院的DB PCLR的另一个增量?5220(61%)。这相当于增量为0.074(SB),另外0.075(DB)QALYS给出?70,000阈值。对于DB作为SB重建的成本效益,KOOS QOL的增量增益必须与非手术治疗相比,KOOS QOL的增量增益与SB重建相同。结论虽然手术重建仅为单独的非手术治疗增加了大量成本,但它可以被认为是成本效益的。双束重建比SB重建更少于成本效率,但可能仍然应该被视为某些患者类别的选择。需要在非手术,SB和DB PCL重建之后寻找结果的随机对照试验。临床相关性是,PCL损伤的手术重建是患有分离的PCL损伤患者的经济有效的治疗方法。在决定如何治疗这些伤害时,应考虑到这一发现。证据III水平。

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