Preoperative nutritional status assessment predicts postoperative outcomes in patients with surgically resected non-small cell lung cancer

摘要

BackgroundAs nutritional status plays an important role in outcomes after surgery, this study evaluated the association between preoperative nutritional status (NS) and postoperative outcomes after major resection for lung cancer. MethodsWe identified 219 patients with a diagnosis of cancer who underwent pulmonary resection from 2010 to 2012. Preoperative NS was assessed by anthropometric and biological parameters, body mass index (BMI), and the Nutritional Risk Index (NRI). We stratified this population into 4 BMI groups:underweight,normal weight,overweightandobeseand 4 NRI groups:well-nourished;mildly malnourished;moderately malnourishedandseverely malnourished. The outcomes measured were postoperative complications; 30-day postoperative mortality; hospital length of stay (LOS), overall survival (OS) and disease-free survival (DFS). We performed both unadjusted analysis and adjusted multivariable analysis, controlling for statistically significant variables. ResultsMean BMI and NRI were, respectively, 26.5?±?4.3 and 112.4?±?3.3. There were no significant differences between BMI categories and resection type, pathological stage, or overall postoperative complications. By contrast, significant differences (p?