Age related depth profiles of human Stratum Corneum barrier-related molecular parameters by confocal Raman microscopy in vivo

Choe ChunSik; Schleusener Johannes; Lademann Juergen; Darvin Maxim E.

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Age related depth profiles of human Stratum Corneum barrier-related molecular parameters by confocal Raman microscopy in vivo

机译：年龄相关的人体角质层屏障相关分子参数的年龄相关深度谱通过体内分子显微镜显微镜

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摘要

In this study, stratum corneum (SC) depth profiles of hydrogen bound water molecule types, intercellular lipid (ICL) ordering, concentration of natural moisturizing factor (NMF) and keratin folding/unfolding properties are investigated in vivo for older (mean 50 years old) and younger (mean 29 years old) human skin using confocal Raman microscopy.

机译：在该研究中，在体内研究了氢气结合水分子类型的氢气结晶水分子类型，细胞间脂质（ICL）排序，天然保湿因子（NMF）和角蛋白折叠/展开特性的深度谱（平均50岁）和年轻（平均29岁）人体皮肤使用共聚焦拉曼显微镜。

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《Mechanisms of Ageing and Development》 |2018年第2018期|共7页
作者
Choe ChunSik; Schleusener Johannes; Lademann Juergen; Darvin Maxim E.;
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作者单位

Humboldt Univ Freie Univ Berlin Charite Univ Med Berlin Charitepl 1 D-10117 Berlin Germany;

Humboldt Univ Freie Univ Berlin Charite Univ Med Berlin Charitepl 1 D-10117 Berlin Germany;

Humboldt Univ Freie Univ Berlin Charite Univ Med Berlin Charitepl 1 D-10117 Berlin Germany;

Humboldt Univ Freie Univ Berlin Charite Univ Med Berlin Charitepl 1 D-10117 Berlin Germany;

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原文格式 PDF
正文语种 eng
中图分类人体生理学;
关键词
Skin barrier function; Intercellular lipids; Keratin; Water; Natural moisturizing factor; Ageing; Hydrogen bonding;

机译：皮肤屏障功能;异细胞脂质;角蛋白;水;天然保湿因子;老化;氢键;

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1. Age related depth profiles of human Stratum Corneum barrier-related molecular parameters by confocal Raman microscopy in vivo [J] . Choe ChunSik, Schleusener Johannes, Lademann Juergen, Mechanisms of Ageing and Development . 2018,第期

机译：年龄相关的人体角质层屏障相关分子参数的年龄相关深度谱通过体内分子显微镜显微镜
2. Non-invasive depth profile imaging of the stratum corneum using confocal Raman microscopy: First insights into the method [J] . AshtikarM., Matth?usC., SchmittM., European journal of pharmaceutical sciences . 2013,第5期

机译：使用共聚焦拉曼显微镜对角质层进行无创深度轮廓成像：对该方法的首次见解
3. MCR Approach Revealing Protein, Water, and Lipid Depth Profile in Atopic Dermatitis Patients' Stratum Corneum via in Vivo Confocal Raman Spectroscopy [J] . Zhang Lesheng, Cambron Tom, Niu Yueqing, Analytical chemistry . 2019,第4期

机译：MCR方法在体内共焦拉曼光谱体内通过体内皮炎患者角质层中的蛋白质，水和脂肪深度分布
4. An Unsupervised Machine Learning Method for Delineating Stratum Corneum in Reflectance Confocal Microscopy Stacks of Human Skin In Vivo [C] . Alican Bozkurt, Kivanc Kose, Christi A. Fox, Photonic therapeutics and diagnostics XII . 2016

机译：在人体皮肤反射共聚焦显微镜下描绘角质层的无监督机器学习方法
5. Exploring the Structure of the Stratum Corneum Lipid Matrix via Molecular Dynamics Simulations [D] . Moore, Timothy C. 2018

机译：通过分子动力学模拟探索角质层脂质基质的结构
6. Non-invasive depth profiling of the stratum corneum in vivo using confocal Raman microscopy considering the non-homogeneous distribution of keratin [O] . Maxim E. Darvin, Chun-Sik Choe, Johannes Schleusener, 2019

机译：考虑角蛋白的非均匀分布使用共聚焦拉曼显微镜对角质层进行体内非侵入性深度分析
7. In vivo confocal Raman microscopic determination of depth profiles of the stratum corneum lipid organization influenced by application of various oils [O] . ChunSik Choe, Johannes Schleusener, Jürgen Lademann, 2017

机译：体内共焦拉曼显微镜测定各种油施用地层基层脂质组织的深度谱

Age related depth profiles of human Stratum Corneum barrier-related molecular parameters by confocal Raman microscopy in vivo

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