METHOD FOR DETECTING A PROTEIN-COATED METAL NANOPARTICLE INSIDE A SINGLE CELL USING A Z-DEPTH DEPENDENT CONFOCAL SURFACE-ENHANCED RAMAN SCATTERING AND A DARK-FIELD MICROSCOPY TECHNIQUE

摘要

PURPOSE: A method for detecting a protein-coated metal nanoparticle inside a single cell using a z-depth dependent confocal surface-enhanced Raman scattering and a dark-field microscopy technique informs absorption inside a cell of a metal nano particle within an A549 cell and behavioral characteristic thereof by using a super spectral imaging technique and a SERS(Surface Enhanced Raman Scattering) combined with a DFM(Dark-Field Microscopy).;CONSTITUTION: A method for detecting a protein-coated metal nanoparticle inside a single cell is as follows. A protein-coated metal nanoparticle is manufactured. The nanoparticle is absorbed inside a cell and detects the absorbed nanoparticle by using a dark-field microscope technique and a z-depth dependent confocal surface-enhanced Raman scattering.;COPYRIGHT KIPO 2012