Synthesis of pyrano[3,4-c]thieno[3,2-e][1,2,4]triazolo[4,3-a]pyridines, representatives of a new fused heterocyclic system

Paronikyan Ervand G.; Dashyan Shushanik Sh.; Mamyan Suren S.

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Synthesis of pyrano[3,4-c]thieno[3,2-e][1,2,4]triazolo[4,3-a]pyridines, representatives of a new fused heterocyclic system

机译：吡喃[3,4-c]噻吩的合成[3,2-e] [1,2,4]三唑唑[4,3-a]吡啶，一种新的融合杂环体系的代表

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摘要

New effective synthesis of functionalized pyrano[3,4-c]thieno[3,2-e][1,2,4]triazolo[4,3-a]pyridines comprises nucleophilic substitution in 8-morpholino-6-thioxopyrano[3,4-c]pyridine5-carbonitrile with hydrazine hydrate followed by sequential heterocyclization with formic acid and chloroacetic acid derivatives.

机译：官能化吡喃的新有效合成[3,4-c]噻吩[3,2-e] [1,2,4]三唑唑[4,3-a]吡啶包含8-晶啉-6-硫代吡喃的亲核取代[3 ，4-C]吡啶5-碳腈，肼水合物，然后用甲酸和氯乙酸衍生物顺序杂环化。

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来源
《Mendeleev Communications 》 |2020年第2期| 共2页
作者
Paronikyan Ervand G.; Dashyan Shushanik Sh.; Mamyan Suren S.;
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作者单位

Natl Acad Sci Republ Armenia Sci Technol Ctr Organ &

Pharmaceut Chem Yerevan 0014 Armenia;

Natl Acad Sci Republ Armenia Sci Technol Ctr Organ &

Pharmaceut Chem Yerevan 0014 Armenia;

Natl Acad Sci Republ Armenia Sci Technol Ctr Organ &

Pharmaceut Chem Yerevan 0014 Armenia;

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原文格式 PDF
正文语种 eng
中图分类化学 ;
关键词
pyrano3; 4-cpyridines; triazolo4; 3-apyridines; pyrano3; 4-cthieno3; 2-e1; 2; 4triazolo4; 3-apyridines; hydrazines; thiones; heterocyclization; alkylation;

机译：吡喃[3;4-c]吡啶;三唑唑[4;3-a]吡啶;吡喃[3;4-c] Thieno [3;2-e] [1;2;4]三唑[4;3-a 吡啶;肼;杂色;杂环;烷基化;

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1. Synthesis of pyrano[3,4-c]thieno[3,2-e][1,2,4]triazolo[4,3-a]pyridines, representatives of a new fused heterocyclic system [J] . Paronikyan Ervand G., Dashyan Shushanik Sh., Mamyan Suren S. Mendeleev Communications . 2020 ,第2期

机译：吡喃[3,4-c]噻吩的合成[3,2-e] [1,2,4]三唑唑[4,3-a]吡啶，一种新的融合杂环体系的代表
2. Derivatives of a new heterocyclic system - pyrano[3,4-c][1,2,4]triazolo[4,3-a]pyridines: synthesis, docking analysis and neurotropic activity [J] . Ervand G. Paronikyan, Anthi Petrou, Maria Fesatidou, MedChemComm . 2019 ,第8期

机译：新型杂环系统的衍生物 - 吡喃[3,4-C] [1,2,4]三唑唑[4,3-A]吡啶：合成，对接分析和神经疗法活性
3. THE SYNTHESIS OF NOVEL POLYCYCLIC HETEROCYCLIC RING SYSTEMS VIA PHOTOCYCLIZATION .19. THIENO[3',2'/4,5]THIENO[2,3-C]-NAPHTHO[1,2-F]QUINOLINE, THIENO[3',2'/4,5]THIENO[2,3-C]NAPHTHO[1,2-F][1,2,4]TRIAZOLO[4,3-A]QUINOLIN E AND THIENO[3',2'/4,5]-THIENO[2, [J] . Luo JK., Castle RN., Federspiel RF. Journal of Heterocyclic Chemistry: The International Journal of Heterocyclic Chemistry . 1997 ,第5期

机译：通过光环化合成新型多环杂环环系统.19。锡诺[3'，2'/ 4,5]锡诺[2,3-C]-萘基[1,2-F]喹诺啉，锡诺[3'，2'/ 4,5]锡诺[2,3-C ] NAPHTHO [1,2-F] [1,2,4]三唑[4,3-A]喹诺酮E和噻吩并[3'，2'/ 4,5]-噻吩并[2，
4. Synthesis of the 3,6-dinitro-1,2,4triazolo 4,3-b1,2,4triazolate anion and characterization of its energetic salts [C] . Matthew Gettings, Matthias Zeller, Edward Byrd, Seminar on new trends in research of energetic materials . 2020

机译：3,6-二硝基-1,2,4三唑4,3-b 1,2,4三唑酸根阴离子的合成及其高能盐的表征
5. Synthesis of Fused Triazolo-Pyridobenzodiazepine Analogs for Use as Potential Atypical Antipsychotic Treatments in Schizophrenia. [D] . Sheehan, Megan. 2016

机译：融合的Triazolo-吡啶基苯并二氮杂pine类似物的合成，可用作精神分裂症的潜在非典型抗精神病药物。
6. Derivatives of a new heterocyclic system – pyrano34-c124triazolo43-apyridines: synthesis docking analysis and neurotropic activity [O] . Ervand G. Paronikyan, Anthi Petrou, Maria Fesatidou, 2019

机译：新的杂环系统的衍生物 - 吡喃34-C 124三唑唑43-A吡啶：合成对接分析和神经疗法活性
7. Synthesis and Biological Activity of Novel Thieno 2,3-d 1,2,4 triazolo 4,3-a pyrimidine and Pyrazolo 3,4-c pyrazole Derivatives [O] . 2012

机译：新型噻吩的合成和生物活性2,3-d 1,2,4三唑唑4,3-A嘧啶和吡唑3,4-C吡唑衍生物

Synthesis of pyrano[3,4-c]thieno[3,2-e][1,2,4]triazolo[4,3-a]pyridines, representatives of a new fused heterocyclic system

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