By downregulating transcription of PARP1, CDK4/6 inhibitors sensitise human lung cancer cells to oxidative stress-induced DNA damage triggered by WP631 and etoposide

著录项

• 来源
  《Free Radical Biology and Medicine: The Official Journal of the Oxygen Society》 |2017年第2017期|共1页
• 作者

  Tempka Dominika; Tokarz Paulina; Chmielewska Kinga; Pietrzak Julita; Robaszkiewicz Agnieszka Zdzislawa;

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• 作者单位

  Univ Lodz Inst Biophys Dept Gen Biophys Pomorska 141-143 PL-90236 Lodz Poland;

  Univ Lodz Inst Biochem Dept Mol Genet Pomorska 141-143 PL-90236 Lodz Poland;

  Univ Lodz Inst Biophys Dept Gen Biophys Pomorska 141-143 PL-90236 Lodz Poland;

  Univ Lodz Inst Biophys Dept Gen Biophys Pomorska 141-143 PL-90236 Lodz Poland;

  Univ Lodz Inst Biophys Dept Gen Biophys Pomorska 141-143 PL-90236 Lodz Poland;

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• 收录信息
• 原文格式 PDF
• 正文语种 eng
• 中图分类 生物化学;
• 关键词

  CDK4/6 inhibitors; cancer; PARP1; DNA damage; histone epigenetic marks;

  机译：CDK4 / 6抑制剂;癌症;PARP1;DNA损伤;组蛋白表观遗传痕迹;