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Evaluation of the RayStation electron Monte Carlo dose calculation algorithm

机译:射线电子蒙特卡洛剂量计算算法评价

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The aim of this work was to evaluate the accuracy of the RayStation treatment planning system electron Monte Carlo algorithm against measured data for a range of clinically relevant scenarios. This was done by comparing measured percentage depth dose data (PDD) in water, profiles at oblique incidence and with heterogeneities in the beam path, and output factor data and that generated using the RayStation treatment planning system Monte Carlo VMC++ based calculation algorithm. While electron treatments are widely employed in the radiotherapy setting accurate modelling is challenging (TPS) in the presence of patient being both heterogeneous and nonrectangular. Watertank-based measurements were made on a Varian TrueBeam linear accelerator covering electron beam energies 6 to 18 MeV. These included both normal and oblique incidence, heterogeneous geometries, and irregular shaped cut-outs. The measured geometries were replicated in RayStation and the Monte Carlo dose calculation engine used to generate dosimetric data for comparison against measurement in what were considered clinically relevant settings. Water-based PDDs and profile comparisons showed excellent agreement for all electron beam energies. Profiles measured with oblique beam incidence demonstrated acceptable agreement to the treatment planning system calculations although the correspondence worsened as the angle increased with the planning system overestimating the dose in the shoulder region. Profile measurements under inhomogeneities were generally good. The planning system had a tendency to overestimate dose under the heterogeneity and also demonstrated a broader penumbra than measurement. Of the 170 different output factors calculated in RayStation over the range of electron energies commissioned, 141 were within +/- 3% of measured values and 164 within +/- 5%. Four of the 6 comparisons beyond 5% were at 18 MeV and all had a cut-out edge within 3 cm of the beam central axis/measurement point. The RayStation implementation of a VMC++ electron Monte Carlo dose calculation algorithm shows good agreement with measured data for a range of scenarios studied and represented sufficient accuracy for clinical use. Crown Copyright (C) 2019 Published by Elsevier Inc. on behalf of American Association of Medical Dosimetrists. All rights reserved.
机译:这项工作的目的是评估射线处理计划系统电子蒙特卡罗算法的准确性,针对一系列临床相关场景进行测量数据。这是通过将测量的百分比深度剂量数据(PDD)在水中进行比较来完成,倾斜入射和光束路径中的异质性,以及使用射线处理计划系统蒙特卡罗VMC ++基于计算算法产生的异质性。虽然电子处理广泛用于放射疗法设置,但准确的建模在存在患者的情况下是具有异质和非抗体的挑战(TPS)。覆盖电子束能量6至18 MeV的Varian Truebeam线性加速器进行了基于Watertank的测量。这些包括正常和倾斜的入射,异质几何形状和不规则形状的切除。测量的几何形状被复制在射线和蒙特卡罗剂量计算引擎中,用于生成剂量测量数据,以便在被认为是临床相关的设置的情况下进行比较。基于水的PDD和简档比较显示了所有电子束能量的良好协议。用斜梁发病率测量的曲线显示了对治疗计划系统计算的可接受的一致性,尽管随着角度的增加而变得令人厌恶,但随着肩部区域中的剂量估计剂量的规划系统而恶化。在不均匀性下的轮廓测量通常很好。规划系统倾向于在异质性下估量剂量,并且还表明了比测量更广泛的半影。在射线上计算的170个不同的输出因子,在委托的电子能量范围内,141次在测量值的+/- 3%内,164内+/- 5%。超过5%的6个比较中的四个是18 mev,并且所有在梁中心轴/测量点的3厘米内都有一个切口边缘。 VMC ++电子蒙特卡洛剂量计算算法的射线实现显示了与所学习的一系列场景的测量数据良好的一致性,并且代表了足够的临床用途。皇冠版权(c)2019年由elsevier Inc.发布代表美国医疗剂量分子师协会。版权所有。

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