Does MMR status in endometrial cancer influence response to adjuvant therapy?

Kim Soyoun Rachel; Pina Annick; Albert Arianne; McAlpine Jessica; Wolber Robert; Gilks C. Blake; Kwon Janice S.

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Does MMR status in endometrial cancer influence response to adjuvant therapy?

机译：内膜癌中的MMR状态是否会影响对佐剂治疗的反应？

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Objective. Mismatch repair (MMR) deficiency occurs in 20-40% of endometrial cancers but its therapeutic implication remains uncertain. Our objective was to compare clinical outcomes after adjuvant therapy between MMR deficient and proficient endometrial cancers from a population-based study.

机译：客观的。不匹配修复（MMR）缺乏症发生在20-40％的子宫内膜癌中，但其治疗暗示仍然不确定。我们的目的是在群体缺乏和巨大的子宫内膜癌症之间从基于人群的研究进行比较辅助治疗后的临床结果。

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来源
《Gynecologic Oncology: An International Journal》 |2018年第1期|共6页
作者
Kim Soyoun Rachel; Pina Annick; Albert Arianne; McAlpine Jessica; Wolber Robert; Gilks C. Blake; Kwon Janice S.;
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作者单位

Univ British Columbia Fac Med Dept Obstet &

Gynecol Vancouver BC Canada;

BC Canc Agcy Vancouver BC Canada;

Womens Hlth Res Inst Vancouver BC Canada;

BC Canc Agcy Vancouver BC Canada;

BC Canc Agcy Vancouver BC Canada;

BC Canc Agcy Vancouver BC Canada;

BC Canc Agcy Vancouver BC Canada;

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原文格式 PDF
正文语种 eng
中图分类肿瘤学;
关键词
Endometrial cancer; Mismatch repair; Recurrence;

机译：子宫内膜癌;不匹配修复;再次发生;

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专利

1. Does MMR status in endometrial cancer influence response to adjuvant therapy? [J] . Kim Soyoun Rachel, Pina Annick, Albert Arianne, Gynecologic Oncology: An International Journal . 2018,第1期

机译：内膜癌中的MMR状态是否会影响对佐剂治疗的反应？
2. Do comorbidity influences acute toxicity and outcome in elderly patients with endometrial cancer treated by adjuvant radiotherapy plus brachytherapy? [J] . FiorentinoA., ChiumentoC., FuscoV. Clinical & translational oncology : . 2013,第8期

机译：合并症是否影响辅助放疗加近距离放射治疗的老年子宫内膜癌患者的急性毒性和预后？
3. Mismatch repair status and outcomes after adjuvant therapy in patients with surgically staged endometrial cancer. [J] . Resnick KE, Frankel WL, Morrison CD, Gynecologic Oncology: An International Journal . 2010,第2期

机译：外科手术分期的子宫内膜癌患者辅助治疗后的错配修复状态和结果。
4. Determining the importance of parameters extracted from multi-parametric MRI in the early prediction of the response to neo-adjuvant chemotherapy in breast cancer [C] . Amirhessam Tahmassebi, Katja Pinker-Domenig, Georg Wengert, SPIE Medical Imaging Conference . 2018

机译：确定从多参数MRI提取的参数在乳腺癌新辅助化疗反应的早期预测中的重要性
5. Combining biomarkers and clinicopathologic factors for prediction of response to adjuvant chemotherapy for breast cancer: Cox model and Support Vector Machine (SVM) methods. [D] . Liu, Xudong. 2010

机译：结合生物标志物和临床病理因素预测乳腺癌对辅助化疗的反应：Cox模型和支持向量机（SVM）方法。
6. Mismatch repair status and outcomes after adjuvant therapy in patients with surgically staged endometrial cancer [O] . Kimberly E. Resnick, Wendy L. Frankel, Carl D. Morrison, -1

机译：手术分阶段子宫内膜癌患者辅助治疗后不匹配修复状态和结果
7. Adjuvant Radiotherapy and/or Chemotherapy for Endometrial Cancer, Status as at 2019 [O] . Günter Emons, Clemens Tempfer, Marco Johannes Battista, 2019

机译：辅助放射治疗和/或化疗用于子宫内膜癌，其现状为2019年

Does MMR status in endometrial cancer influence response to adjuvant therapy?

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