Quality of life and swallowing with standard chemoradiotherapy versus accelerated radiotherapy and panitumumab in locoregionally advanced carcinoma of the head and neck: A phase III randomised trial from the Canadian Cancer Trials Group (HN.6)

Ringash Jolie; Waldron John N.; Siu Lillian L.; Martino Rosemary; Winquist Eric; Wright Jim R.; Nabid Abdenour; Hay John H.; Hammond Alex; Sultanem Khalil; Hotte Sebastien; Leong Carson; El-Gayed Ali Abdel Halim; Naz Farah; Ramchandar Kevin; Owen Timothy E.; Montenegro Alexander; OSullivan Brian; Chen Bingshu E.; Parulekar Wendy R.

首页> 外文期刊>European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) >Quality of life and swallowing with standard chemoradiotherapy versus accelerated radiotherapy and panitumumab in locoregionally advanced carcinoma of the head and neck: A phase III randomised trial from the Canadian Cancer Trials Group (HN.6)

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Quality of life and swallowing with standard chemoradiotherapy versus accelerated radiotherapy and panitumumab in locoregionally advanced carcinoma of the head and neck: A phase III randomised trial from the Canadian Cancer Trials Group (HN.6)

机译：用标准化学疗法的生活质量和吞咽促进放疗和颈部型头颈癌的加速放疗和Panitumumab：来自加拿大癌症试验组的III期随机试验（HN.6）

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摘要

Aim: To compare quality of life (QOL) between standard (SFX) chemoradiotherapy (arm A) and altered fractionation radiotherapy (AFX) with panitumumab (PMab; arm B).

机译：目的：将标准（SFX）化学疗法（ARM A）与Panitumumab（PMAB; ARM B）的改变分馏放疗（AFX）之间的寿命质量（QOL）进行比较。

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来源
《European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)》 |2017年第2017期|共8页
作者
Ringash Jolie; Waldron John N.; Siu Lillian L.; Martino Rosemary; Winquist Eric; Wright Jim R.; Nabid Abdenour; Hay John H.; Hammond Alex; Sultanem Khalil; Hotte Sebastien; Leong Carson; El-Gayed Ali Abdel Halim; Naz Farah; Ramchandar Kevin; Owen Timothy E.; Montenegro Alexander; OSullivan Brian; Chen Bingshu E.; Parulekar Wendy R.;
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作者单位

Univ Toronto Univ Hlth Network Princess Margaret Canc Ctr Toronto ON Canada;

Univ Toronto Univ Hlth Network Princess Margaret Canc Ctr Toronto ON Canada;

Univ Toronto Univ Hlth Network Princess Margaret Canc Ctr Toronto ON Canada;

Univ Toronto Dept Speech Language Pathol Toronto ON Canada;

London Hlth Sci Ctr London ON Canada;

Juravinski Canc Ctr Hamilton ON Canada;

CHU Sherbrooke Sherbrooke PQ Canada;

British Columbia Canc Agcy Vancouver BC Canada;

London Hlth Sci Ctr London ON Canada;

McGill Univ Ctr Hlth Montreal PQ Canada;

Juravinski Canc Ctr Hamilton ON Canada;

British Columbia Canc Agcy Fraser Valley Ctr Fraser Valley BC Canada;

Saskatoon Canc Ctr Saskatoon SK Canada;

St Johns Hosp Horizon Hlth Network St John NB Canada;

Northwestern Ontario Reg Canc Care Thunder Bay ON Canada;

Northeast Canc Ctr Sudbury ON Canada;

Canadian Canc Trials Grp Kingston ON Canada;

Univ Toronto Univ Hlth Network Princess Margaret Canc Ctr Toronto ON Canada;

Canadian Canc Trials Grp Kingston ON Canada;

Canadian Canc Trials Grp Kingston ON Canada;

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原文格式 PDF
正文语种 eng
中图分类肿瘤学;
关键词
Randomised clinical trial; Phase III clinical trial; Head and neck neoplasms; Intensity-modulated radiation therapy; Cisplatin; Concurrent chemoradiotherapy; Quality of life; Swallowing; Patient-reported outcomes;

机译：随机临床试验;III期临床试验;头部和颈部肿瘤;强度调制的放射疗法;顺铂;同时进行化学疗法;生活质量;吞咽;患者报告的结果;

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1. Quality of life and swallowing with standard chemoradiotherapy versus accelerated radiotherapy and panitumumab in locoregionally advanced carcinoma of the head and neck: A phase III randomised trial from the Canadian Cancer Trials Group (HN.6) [J] . Ringash Jolie, Waldron John N., Siu Lillian L., European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) . 2017,第期

机译：用标准化学疗法的生活质量和吞咽促进放疗和颈部型头颈癌的加速放疗和Panitumumab：来自加拿大癌症试验组的III期随机试验（HN.6）
2. Conventional radiotherapy versus concurrent chemoradiotherapy versus accelerated radiotherapy in locoregionally advanced carcinoma of head and neck: Results of a prospective randomized trial [J] . Ghosh-Laskar Sarbani, Kalyani Nikhil, Gupta Tejpal, Head and neck: Journal for the sciences and specialities of the head and neck . 2016,第2期

机译：局部放疗的头颈部恶性肿瘤的常规放疗，同步放化疗和加速放疗：一项前瞻性随机试验的结果
3. Induction chemotherapy followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in locoregionally advanced nasopharyngeal carcinoma: long-term results of a phase III multicentre randomised controlled trial [J] . Yang Qi, Cao Su-Mei, Guo Ling, European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) . 2019,第期

机译：感应化疗随后通过同时进行化学疗法，单独的同时进行化学疗法在型鼻咽癌中：III期多期式随机对照试验的长期结果
4. NKI-CCRT Corpus - Speech Intelligibility Before and After Advanced Head and Neck Cancer Treated with Concomitant Chemoradiotherapy [C] . R.P. Clapham, L. van der Molen, R.J.J.H. van Son, International conference on language resources and evaluation . 2012

机译：NKI-CCRT语料库-伴随放化疗治疗晚期头颈癌前后的语音清晰度
5. Evaluation of a randomized clinical trial of a psychoeducational intervention on long-term quality of life, negative affect, progression and survival in head and neck cancer patients. [D] . Trevino, Lara A. 2011

机译：心理教育干预对头颈部癌症患者的长期生活质量，负面影响，进展和生存的随机临床试验评估。
6. Randomized phase III trial of concurrent chemoradiotherapy vs accelerated hyperfractionation radiotherapy in locally advanced head and neck cancer [O] . Imjai Chitapanarux, Ekkasit Tharavichitkul, Pimkhuan Kamnerdsupaphon, 2013

机译：同时进行放化疗与加速超分割放疗在局部晚期头颈部癌中的随机III期试验
7. Panitumumab plus radiotherapy versus chemoradiotherapy in patients with unresected, locally advanced squamous-cell carcinoma of the head and neck (CONCERT-2): a randomised, controlled, open-label phase 2 trial [O] . Giralt Jordi, Trigo Jose, Nuyts Sandra, 2015

机译：帕尼单抗联合放疗与放化疗联合治疗未切除的局部晚期头颈部鳞状细胞癌（CONCERT-2）：一项随机，对照，开放标签的2期试验

Quality of life and swallowing with standard chemoradiotherapy versus accelerated radiotherapy and panitumumab in locoregionally advanced carcinoma of the head and neck: A phase III randomised trial from the Canadian Cancer Trials Group (HN.6)

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