P-626: Red blood cell parameters in older Turkish adults: age and gender relationship

摘要

Introduction: There is currently a controversy of whether elderly people (C 65) have an age-related physiologic decline in red cell parameters. The objective of this study was to determine physiologic hematological parameters and analyze the relationship with age and gender. Methods: Data of patients over 65 were obtained from digital hospital files. Hemoglobin (Hb), hemotocrit (Hct), red blood cell (RBC), mean corpusculer volume (MCV), red blood cell distribution width (RDW), mean corpuscular hemoglobin concentration (MCHC) values were analyzed. Exclusion criteria were hematologic disease history, high LDH and reticulocyte level, GFR < 60 mL/min/1.73 m~2 , high CRP levels and low transferrin saturation. Results: 212 participants were included (Male:76, woman: 136). 104 patients were 65-74 years old and 108 patients aged ≥ 75 years. Mean Hb and Htc were 13.1 ± 1.05 g/dl and 39.9 ± 3.1 g/dl in women and 14.2 ± 1.46 g/dl, 42.3 ± 3.9 in men, respectively. Mean RBC was 4.63 ± 0.43 10~6/μL in women, 4.77 ± 0.46 10~6/μL in men. Mean MCHC, MCV, RDW levels were 33.1 g/dL, 86.5 fL, 13.7 106/ μL in women and 33.7 g/dL, 88.8 fL, 13.4 10~6 /μL in men, respectively. As the age increased Hb, Hct and RBC levels were decreased in both males and females but relationship was statistically significant only in males (p < 0.001). No significant difference was found between mean values of MCV, MCHC, and RDW in both groups. Conclusion: There are few studies about red blood cell parameters in Turkish patients over 65. In this study we aimed to contribute to geriatric literature.