Squamous cell carcinoma at a colostomy site

摘要

Introduction: The development of a malignancy at a stoma site is an extremely rare event, with a rate reported at 2-4 of every 1,000 cases. Most of the cases are adenocarcinomas, with only a few squamous cell carcinomas (SCCs) reported as of today. Case Report: The authors present a case of a second primary SCC developing at the colostomy site nine months after colostomy formation. Discussion: The literature research revealed seven cases published in English. These cases presented with a minimum of ten years following stoma formation, and most of them developed in the setting of inflammatory bowel disease. It has been proposed that chronic chemical irritation at the stoma mucocutaneous junction may he carcinogenic. Conclusion: Patients with a stoma should be properly educated for early identification of problems. Additionally, a biopsy should be taken of any suspicious lesion in order to rule out malignant transformation.