Physiologically based pharmacokinetic modeling (PBPK's) prediction potential in clinical pharmacology decision making during pregnancy

Eke Ahizechukwu C.; Gebreyohannes Rahel D.

首页> 外文期刊>International journal of gynecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics >Physiologically based pharmacokinetic modeling (PBPK's) prediction potential in clinical pharmacology decision making during pregnancy

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Physiologically based pharmacokinetic modeling (PBPK's) prediction potential in clinical pharmacology decision making during pregnancy

机译：怀孕期间临床药理学决策中的生理基础的药代动力学建模（PBPK）预测潜力

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摘要

Physiologically based pharmacokinetic modeling's prediction potential is critical in clinical pharmacology decision making during pregnancy.

机译：基于生理学的药代动力学建模的预测潜力对于妊娠期间的临床药理学决策至关重要。

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《International journal of gynecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics》 |2020年第3期|共3页
作者
Eke Ahizechukwu C.; Gebreyohannes Rahel D.;
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作者单位

Johns Hopkins Univ Sch Med Dept Gynecol &

Obstet Div Maternal Fetal Med Baltimore MD 21205 USA;

Addis Ababa Univ Coll Med Dept Gynecol &

Obstet Addis Ababa Ethiopia;

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原文格式 PDF
正文语种 eng
中图分类妇产科学;
关键词
Bictegravir; Doravirine; Physiologically based pharmacokinetic modeling; Prediction; Pregnancy;

机译：Bictegravir;Doravirine;基于生理基础的药代动力学建模;预测;怀孕;

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专利

1. Physiologically based pharmacokinetic modeling (PBPK's) prediction potential in clinical pharmacology decision making during pregnancy [J] . Eke Ahizechukwu C., Gebreyohannes Rahel D. International journal of gynecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics . 2020,第3期

机译：怀孕期间临床药理学决策中的生理基础的药代动力学建模（PBPK）预测潜力
2. Prediction of pharmacokinetics and drug-drug interaction potential using physiologically based pharmacokinetic (PBPK) modeling approach: A case study of caffeine and ciprofloxacin [J] . Park Min-Ho, Shin Seok-Ho, Byeon Jin-Ju, The Korean Journal of Physiology & Pharmacology . 2017,第1期

机译：基于生理学的药代动力学（PBPK）建模方法预测药代动力学和药物相互作用的可能性：咖啡因和环丙沙星的案例研究
3. PHYSIOLOGICALLY BASED PHARMACOKINETIC (PBPK) MODEL PREDICTIONS OF CYP MEDIATED DDIS: POTENTIAL INTERACTIONS BETWEEN ICA-105665 AND CYP ENZYME INDUCERS. [J] . Callegari E., Dua P., Rigdon G., Clinical Pharmacology and Therapeutics . 2015,第S1期

机译：CYP介导的DDIS的基于生理的药动学（PBPK）模型预测：ICA-105665与CYP酶诱导剂之间的潜在相互作用。
4. Exploration of potential susceptibility of the older rodent population to two solvents using physiologically based pharmacokinetic (PBPK) transport models [C] . Marina V.Evans, Elise M.Westmeyer, Michael Delp, Bioengineering conference . 1999

机译：使用生理学药代动力学（PBPK）传输模型探索老年啮齿动物对两种溶剂的潜在敏感性
5. Application of physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) model in studying the carcinogenic potential of hexacholorobenzene, PCB 126, and their mixture. [D] . Lu, Yasong. 2006

机译：基于生理学的药代动力学/药效学（PBPK / PD）模型在研究六氯苯，PCB 126及其混合物的致癌潜力中的应用。
6. Prediction of pharmacokinetics and drug-drug interaction potential using physiologically based pharmacokinetic (PBPK) modeling approach: A case study of caffeine and ciprofloxacin [O] . Min-Ho Park, Seok-Ho Shin, Jin-Ju Byeon, 2017

机译：基于生理学药代动力学（PBPK）建模方法的药代动力学和药物相互作用的预测：以咖啡因和环丙沙星为例
7. Prediction of drug disposition in infants and children by means of physiologically based pharmacokinetic (PBPK) modelling: theophylline and midazolam as model drugs [O] . Björkman, Sven 2005

机译：通过基于生理的药代动力学（PBPK）模型预测婴幼儿的药物处置：以茶碱和咪达唑仑为模型药物
8. Availability of Acute and/or Subacute Toxicokinetic Data for Select Compounds for the Rat and Physiologically Based Pharmacokinetic (PBPK) Models for Rats and Humans for Those Compounds. [R] . Sweeney, L. M., Goodwin, M. R. 2017

机译：用于大鼠的选择化合物的急性和/或亚急性毒代动力学数据的可用性和用于那些化合物的大鼠和人的基于生理学的药代动力学（pBpK）模型。

Physiologically based pharmacokinetic modeling (PBPK's) prediction potential in clinical pharmacology decision making during pregnancy

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