The Effect of Thymoquinone on Apoptosis of SK-OV-3 Ovarian Cancer Cell by Regulation of Bcl-2 and Bax

Liu Xiaoli; Dong Jinhu; Cai Wangyu; Pan Ying; Li Ruili; Li Bing

首页> 外文期刊>International journal of gynecological cancer: official journal of the International Gynecological Cancer Society >The Effect of Thymoquinone on Apoptosis of SK-OV-3 Ovarian Cancer Cell by Regulation of Bcl-2 and Bax

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The Effect of Thymoquinone on Apoptosis of SK-OV-3 Ovarian Cancer Cell by Regulation of Bcl-2 and Bax

机译：通过调节Bcl-2和Bax对SK-OV-3卵巢癌细胞凋亡的胸腺酮对SK-OV-3卵巢癌细胞的影响

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摘要

Objective: We aim to determine how cisplatin, thymoquinone (TQ), and combination regimen can affect apoptosis of cultured SK-OV-3 cells. We also want to explore the mechanism of these influences on the cells' apoptosis by Bcl-2 and Bax gene.

机译：目的：我们的目标是确定顺铂，胸腺酮（TQ）和组合方案如何影响培养的SK-OV-3细胞的凋亡。我们还希望探讨BCL-2和BAX基因对细胞凋亡的影响的机制。

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来源
《International journal of gynecological cancer: official journal of the International Gynecological Cancer Society》 |2017年第8期|共6页
作者
Liu Xiaoli; Dong Jinhu; Cai Wangyu; Pan Ying; Li Ruili; Li Bing;
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作者单位

Henan Prov Hosp Tradit Chinese Med Zhengzhou Henan Peoples R China;

Nan Yang First Peoples Hosp Nanyang Peoples R China;

Heilongjiang Univ Chinese Med Harbin Heilongjiang Peoples R China;

Xinxiang Med Univ Affiliated Hosp 3 Xinxiang Peoples R China;

Henan Univ Chinese Med Zhengzhou Henan Peoples R China;

Fudan Univ Jinshan Hosp Shanghai Peoples R China;

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原文格式 PDF
正文语种 eng
中图分类肿瘤学;
关键词
Thymoquinone; Cisplatin; Ovarian cancer; Apoptosis; Cell cycle;

机译：胸腺量;顺铂;卵巢癌;凋亡;细胞周期;

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1. The Effect of Thymoquinone on Apoptosis of SK-OV-3 Ovarian Cancer Cell by Regulation of Bcl-2 and Bax [J] . Liu Xiaoli, Dong Jinhu, Cai Wangyu, International journal of gynecological cancer: official journal of the International Gynecological Cancer Society . 2017,第8期

机译：通过调节Bcl-2和Bax对SK-OV-3卵巢癌细胞凋亡的胸腺酮对SK-OV-3卵巢癌细胞的影响
2. Adenosine induces cell cycle arrest and apoptosis via cyclinD1/Cdk4 and Bcl-2/Bax pathways in human ovarian cancer cell line OVCAR-3. [J] . Saeid Shirali, Mahmoud Aghaei, Mahdi Shabani, Tumour biology : . 2013,第2期

机译：腺苷通过人卵巢癌细胞系OVCAR-3中的cyclinD1 / Cdk4和Bcl-2 / Bax途径诱导细胞周期停滞和凋亡。
3. Sanguinarine induces apoptosis of HT-29 human colon cancer cells via the regulation of Bax/Bcl-2 ratio and caspase-9-dependent pathway [J] . LeeJ.S., JungW.-K., JeongM.H., International journal of toxicology . 2012,第1期

机译：Sanguinarine通过调节Bax / Bcl-2比和caspase-9依赖性途径诱导HT-29人结肠癌细胞凋亡
4. PATHOPHYSIOLOGICAL EFFECTS OF THYMOQUINONE AND EPIGALLOCATECHIN-3-GALLATE ON SK-OV-3 OVARIAN CANCER LIKE CELL LINE [C] . Jennifer L. Harpole, Michelle Tucci, Hamed Benghuzzi International ISA biomedical sciences instrumentation symposium;International Society of Automation;Annual Rocky Mountain bioengineering symposium . 2015

机译：胸腺嘧啶酮和表没食子儿茶素-3-没食子酸酯对SK-OV-3卵巢癌细胞样细胞系的影响
5. Investigating the molecular mechanisms of Bcl-2 and Bax in the regulation of apoptosis. [D] . Annis, Matthew G. 2004

机译：研究Bcl-2和Bax调控细胞凋亡的分子机制。
6. Simvastatin inhibits cancer cell growth by inducing apoptosis correlated to activation of Bax and down-regulation of BCL-2 gene expression [O] . CARMINE SPAMPANATO, SALVATORE DE MARIA, MADDALENA SARNATARO, -1

机译：辛伐他汀通过诱导与Bax激活和BCL-2基因表达下调相关的凋亡来抑制癌细胞的生长
7. Amygdalin Induces Apoptosis through Regulation of Bax and Bcl-2 Expressions in Human DU145 and LNCaP Prostate Cancer Cells [O] . Hyun-Kyung Chang, Mal-Soon Shin, Hye-Young Yang, 2006

机译：Amygdalin通过在人DU145和LNCAP前列腺癌细胞中调节Bax和Bcl-2表达的调节诱导细胞凋亡
8. Selection of Aptamers for CED-9/Bcl-2 Family Cell Death Regulations and Their Application in Study of Apoptosis Regulation and Drug Design for Breast Cancer [R] . Xue, D. , Yang, C. , Camp, N. 2005

机译：CED-9 / Bcl-2家族细胞死亡调控适配体的选择及其在乳腺癌细胞凋亡调控和药物设计研究中的应用

The Effect of Thymoquinone on Apoptosis of SK-OV-3 Ovarian Cancer Cell by Regulation of Bcl-2 and Bax

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