A preliminary study on the antibacterial effects of ethanolic extract of Psidium guajava leaves on Bacteria isolated from urinary tract infection with special reference to Escherichia coli and Staphylococcus aureus

摘要

Increasing bacterial resistance against antibiotics, used in urinary tract infection (UTI) is an emerging problem for human health. Therefore, this study was aimed at using ethanolic extract of leaves of Psidium guajava (guava) and assessing their effect in vitro on bacterial agents causing urinary tract infections, and also compared the effect of these extracts with common antibiotics being used in the treatment of urinary tract infection.In an experimental design, the Escherichia coli (E.coli) and Staphylococcus aureus (S. aureus) were isolated from the urine of UTI patients. Antibacterial effects of the leaves extract against these bacteria were evaluated by well diffusion method and resistance of antibiotics against isolates was evaluated by using hexa UTI disc 4 (Himedia pvt limited). Ampicillin, gentamycin, nitrofurantoin, ciprofloxacin, nalidixic acid, co-trimoxazole were the antibiotics present in hexa UTI disc-4, tested against E. coli and S. aureus. Among these ciprofloxacin showed greater zone of inhibition compared to ethanolic extract of guava leaves.