ANTIBACTERIAL ACTIVITY OF GUAVA (PSIDIUM GUAJAVA L.) EXTRACTS ON STAPHYLOCOCCUS AUREUS ISOLATED FROM PATIENTS WITH URINARY TRACT INFECTIONS ATTENDING A TERTIARY-CARE HOSPITAL

摘要

The uses of herbal treatment are one of the possible ways to treat diseases caused by multi drug resistant bacteria. In this study, the phytochemical and antimicrobial effect of Psidium guajava (l.) leaf and stem extracts were investigated using well diffusion method against Staphylococcus aureus isolates recovered from urine sample of patients with urinary tract infection (UTI) attending Murtala Muhammad Specialist Hospital, Kano. The results revealed that the plant contained some bioactive compounds which includes; Alkaloids, Flavonoids, Anthraquinones, Amino acid, Saponins, Tannins, Reducing sugar, Glycoside and Phenolic compound. The antimicrobial activity of the plant showed that the plant leaf and stem extracts (Ethanolic and Aqueous) had an antibacterial activity against the test isolates with varying mean zones of inhibitions ranging from 10mm to 24mm. However, the organic solvent extract showed more effect compared to the aqueous extract. The present study therefore, suggested that the plant (Psidium guajava L.) can be used as an alternative to chemotherapeutic agents.