Synthesis of Polycyclic Amides via Tandem Rh-III-Catalyzed C-H Activation and Annulation from Dioxazolones and Alkynes

摘要

A highly efficient synthesis of polycyclic amides by a Rh-III-catalyzed cascade cyclization of 3-phenyl-1,4,2-dioxazol-5-one and diphenylacetylene has been developed. This one-pot strategy expanded the application scope of directing groups to dioxazolones.