Molecular surveillance of antimalarial drug resistance related genes in Plasmodium falciparum isolates from Eritrea

摘要

The introduction of artemisinin-based combination therapy has led to extraordinary results in malaria control, however the recent emergence of partial resistance to artemisinin therapy in Southeast Asia jeopardizes these successes. This study aimed at investigating resistance to the antimalarial drugs by evaluating the polymorphisms in the Pfk13, Pfcrt and Pfmdr1 genes in Plasmodium falciparum isolates obtained from patients in Eritrea. (C) 2016 Elsevier B.V. All rights reserved.