Relationship of Echocardiographic Epicardial Fat Thickness and Epicardial Fat Volume by Computed Tomography with Coronary Artery Calcification: Data from the CAESAR Study

摘要

Background and Aims No study has assessed the association between echocardiographic epicardial fat thickness (EFT) and computed tomography (CT)-based epicardial fat volume (EFV) and coronary artery calcification. The aim of this study is to evaluate the association between EFT and EFV and coronary artery calcification. Methods Among the 2,299 individuals enrolled in the CArdiometabolic risk, Epicardial fat, and Subclinical Atherosclerosis Registry (CAESAR) study, 2,276 (1,851 men; mean age 45?±?8.9?years) who underwent echocardiographic EFT and CT-based EFV measurements and obtained a coronary artery calcium score (CACS) were included in this study. Results The overall prevalence of CAC >0 was 19.3%. EFT was significantly correlated with EFV ( r ?=?0.374, p k statistic showed only slight agreement ( k ?=?0.146, p p ?=?0.001 and 0.042, respectively). Conclusion These results show that EFT and EFV are associated with coronary artery calcification in Korean adults despite the relatively weak correlation between EFT and EFV.