Nickel-Catalyzed Decarboxylative C-Si Bond Formation: A Regioselective Cross-Coupling Between Trialkyl Silanes and alpha,beta-Unsaturated Carboxylic Acids

摘要

This report presents the first example of nickel-catalyzed mild decarboxylative cross-coupling reaction for the regioselective formation of C-Si bond. An easily accessible and significantly stable Ni (dmg)(2) owes the role of key promoter. This reaction is highly functional group tolerant and offers alpha,beta-unsaturated silanes in synthetically useful yields. The reaction gives access to the successful utilization of otherwise difficult trialkyl silanes as coupling partners and operates at a moderate temperature, which is beneficial to deal with highly volatile silanes.