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Inflammation in Neurological Disorders: The Thin Boundary Between Brain and Periphery

机译:神经系统疾病中的炎症:大脑与周边之间的薄边界

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摘要

-brain barrier loses its integrity, as often occurs in the course of these diseases. It has been hypothesized that the perpetual bidirectional flux of inflammatory mediators is not a mere "static" collateral effect of the neurodegeneration, but represents a proactive phenomenon sparking and driving the neuropathological processes. However, the upstream/downstream relationship between inflammatory events and neurological pathology is still unclear.
机译:-Brain屏障失去了完整性,因为在这些疾病的过程中经常发生。 已经假设炎症介质的永久双向通量不是神经变性的“静态”的抵押效应,而是表示引发和驱动神经病理过程的主动现象。 然而,炎症事件和神经病理学之间的上游/下游关系仍然不清楚。

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