Primary leptomeningeal oligodendroglioma with documented progression to anaplasia and t(1;19)(q10;p10) in a child.

摘要

Oligodendrogliomas are infiltrating gliomas typically arising in the cerebral cortex and white matter. Rare examples present with diffuse leptomeningeal involvement in the absence of a clinically/radiologically detectable intra-parenchymal tumor [1-5, 7, 8, 10, 14, 15]. Although oligodendrogliomas are rare in children, most primary leptomeningeal oligodendrogliomas have occurred in the first decade of life (Table 1). We report the case of a 3-year-old girl, who presented with progressive regression of her ability to walk and an increase of cranial circumference.