Recent Advances and Perspectives in Small-molecule TLR Ligands and Their Modulators

Shukla Nikunj M.; Chan Michael; Hayashi Tomoko; Carson Dennis A.; Cottam Howard B.

首页> 外文期刊>ACS medicinal chemistry letters >Recent Advances and Perspectives in Small-molecule TLR Ligands and Their Modulators

【24h】

Recent Advances and Perspectives in Small-molecule TLR Ligands and Their Modulators

机译：小分子TLR配体及其调节剂的最新进展和观点

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Activation of Toll-like receptors (TLRs) located on immune cells leads to induction of immune responses that can be useful in vaccines for infectious diseases, cancer immunotherapy, and autoimmune diseases. Novel TLR signaling pathway modulators can further enhance the efficacy of TLR ligands.

机译：活化位于免疫细胞上的可收费受体（TLR）导致免疫应答的诱导，其可用于传染病，癌症免疫疗法和自身免疫疾病的疫苗中。新型TLR信号通路调节剂可以进一步增强TLR配体的功效。

著录项

来源
《ACS medicinal chemistry letters》 |2018年第12期|共7页
作者
Shukla Nikunj M.; Chan Michael; Hayashi Tomoko; Carson Dennis A.; Cottam Howard B.;
展开▼
作者单位

Univ Calif San Diego Moores Canc Ctr 9500 Gilman Dr La Jolla CA 92093 USA;

Univ Calif San Diego Moores Canc Ctr 9500 Gilman Dr La Jolla CA 92093 USA;

Univ Calif San Diego Moores Canc Ctr 9500 Gilman Dr La Jolla CA 92093 USA;

Univ Calif San Diego Moores Canc Ctr 9500 Gilman Dr La Jolla CA 92093 USA;

Univ Calif San Diego Moores Canc Ctr 9500 Gilman Dr La Jolla CA 92093 USA;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类药学;化学;
关键词
Toll-like receptors; TLR; vaccine; infectious disease; cancer; autoimmune; modulator;

机译：Toll样受体;TLR;疫苗;传染病;癌症;自身免疫;调制器;

相似文献

外文文献
中文文献
专利

1. Recent Advances and Perspectives in Small-molecule TLR Ligands and Their Modulators [J] . Shukla Nikunj M., Chan Michael, Hayashi Tomoko, ACS medicinal chemistry letters . 2018,第12期

机译：小分子TLR配体及其调节剂的最新进展和观点
2. Intestinal Expression of Fas and Fas Ligand Is Upregulated by Bacterial Signaling through TLR4 and TLR5, with Activation of Fas Modulating Intestinal TLR-Mediated Inflammation [J] . Fernandes Philana, ODonnell Charlotte, Lyons Caitriona, The Journal of Immunology: Official Journal of the American Association of Immunologists . 2014,第12期

机译：Fas和Fas配体的肠道表达通过TLR4和TLR5的细菌信号传递而上调，并激活Fas调节肠道TLR介导的炎症。
3. Intestinal Expression of Fas and Fas Ligand Is Upregulated by Bacterial Signaling through TLR4 and TLR5, with Activation of Fas Modulating Intestinal TLR-Mediated Inflammation [J] . Philana Fernandes, Charlotte O’Donnell, Caitriona Lyons, The journal of immunology . 2014,第12期

机译：Fas和Fas配体的肠道表达通过TLR4和TLR5的细菌信号传递而上调，并激活Fas调节肠道TLR介导的炎症。
4. Lanthionine-a new scaffold for TLR-2/TLR-6 ligands with antagonistic activities [C] . Tobias Seyberth, Sohnke Voss, Roland Brock International Peptide Symposium;European Peptide Symposium . 2005

机译：兰尼胺 - 用于TLR-2 / TLR-6配体的新支架，具有拮抗活动
5. Helminth antigens modulate TLR-ligand induced dendritic cell activation. [D] . Kane, Colleen M. 2007

机译：蠕虫抗原调节TLR配体诱导的树突状细胞活化。
6. Recent Advances and Perspectives in Small-moleculeTLR Ligands and Their Modulators [O] . NikunjM. Shukla, Michael Chan, Tomoko Hayashi, 2018

机译：小分子的最新进展和展望TLR配体及其调节剂
7. Recent Advances and Perspectives in Small-molecule TLR Ligands and Their Modulators [O] . Nikunj M. Shukla, Michael Chan, Tomoko Hayashi, 2018

机译：小分子TLR配体及其调节剂中最近的进展和观点

Recent Advances and Perspectives in Small-molecule TLR Ligands and Their Modulators

摘要

著录项

相似文献

相关主题

期刊订阅