25-Hydroxyvitamin D, biomarkers of eosinophilic inflammation, and airway remodeling in children with newly diagnosed untreated asthma

Sypniewska Grazyna; Krintus Magdalena; Fulgheri Gabriele; Siodmiak Joanna; Kuligowska-Prusinska Magdalena; Stepien-Jaszowska Beata; Staszak-Kowalska Radoslawa; Zawadzka-Krajewska Anna; Kierat Szymon; Bergmann Katarzyna; Demkow Urszula

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25-Hydroxyvitamin D, biomarkers of eosinophilic inflammation, and airway remodeling in children with newly diagnosed untreated asthma

机译：25-羟基维生素D，嗜酸性炎症的生物标志物，以及新诊断出未经治疗的哮喘的儿童的气道重塑

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Background: Low 25-hydroxyvitamin D (25[OH] D) and asthma development may be related to airway remodeling and eosinophilia. Periostin is proposed as a key molecule that links remodeling and eosinophilic inflammation.

机译：背景：低25-羟基维生素D（25 [OH] D）和哮喘发育可能与气道重塑和嗜酸性粒细胞有关。提出骨蛋白作为链接重塑和嗜酸性炎症的关键分子。

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来源
《Allergy and asthma proceedings》 |2017年第3期|共8页
作者
Sypniewska Grazyna; Krintus Magdalena; Fulgheri Gabriele; Siodmiak Joanna; Kuligowska-Prusinska Magdalena; Stepien-Jaszowska Beata; Staszak-Kowalska Radoslawa; Zawadzka-Krajewska Anna; Kierat Szymon; Bergmann Katarzyna; Demkow Urszula;
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Nicolaus Copernicus Univ Coll Med Dept Lab Med Sklodowskiej Curie 9 PL-85094 Bydgoszcz Poland;

Nicolaus Copernicus Univ Coll Med Dept Lab Med Sklodowskiej Curie 9 PL-85094 Bydgoszcz Poland;

Nicolaus Copernicus Univ Coll Med Dept Lab Med Sklodowskiej Curie 9 PL-85094 Bydgoszcz Poland;

Nicolaus Copernicus Univ Coll Med Dept Lab Med Sklodowskiej Curie 9 PL-85094 Bydgoszcz Poland;

Nicolaus Copernicus Univ Coll Med Dept Lab Med Sklodowskiej Curie 9 PL-85094 Bydgoszcz Poland;

Childrens Hosp Dept Pediat Pneumonol &

Allergol Bydgoszcz Poland;

Childrens Hosp Dept Pediat Pneumonol &

Allergol Bydgoszcz Poland;

Med Univ Warsaw Dept Pediat Pneumonol &

Allergol Warsaw Poland;

Med Univ Warsaw Dept Lab Diagnost &

Clin Immunol Warsaw Poland;

Nicolaus Copernicus Univ Coll Med Dept Lab Med Sklodowskiej Curie 9 PL-85094 Bydgoszcz Poland;

Med Univ Warsaw Dept Lab Diagnost &

Clin Immunol Warsaw Poland;

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正文语种 eng
中图分类免疫性疾病;
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1. 25-Hydroxyvitamin D, biomarkers of eosinophilic inflammation, and airway remodeling in children with newly diagnosed untreated asthma [J] . Sypniewska Grazyna, Krintus Magdalena, Fulgheri Gabriele, Allergy and asthma proceedings . 2017,第3期

机译：25-羟基维生素D，嗜酸性炎症的生物标志物，以及新诊断出未经治疗的哮喘的儿童的气道重塑
2. Nafamostat mesilate, a potent serine protease inhibitor, inhibits airway eosinophilic inflammation and airway epithelial remodeling in a murine model of allergic asthma. [J] . Ishizaki M, Tanaka H, Kajiwara D, Journal of pharmacological sciences. . 2008,第3期

机译：甲磺酸萘法莫他酯（Nafamostat mesilate）是一种有效的丝氨酸蛋白酶抑制剂，在变应性哮喘的小鼠模型中抑制气道嗜酸性炎症和气道上皮重塑。
3. Nafamostat Mesilate, a Potent Serine Protease Inhibitor, Inhibits Airway Eosinophilic Inflammation and Airway Epithelial Remodeling in a Murine Model of Allergic Asthma [J] . Daisuke Kajiwara, Hiroichi Nagai, Hiroyuki Tanaka, Journal of pharmacological sciences. . 2008,第3期

机译：甲磺酸萘法莫他酯（Nafamostat Mesilate），一种有效的丝氨酸蛋白酶抑制剂，在过敏性哮喘的小鼠模型中抑制气道嗜酸性炎症和气道上皮重塑。
4. Enhancement of Antigen-Induced Eosinophilic Inflammation in the Airways of Mice by Urban Particles in Beijing [C] . Miao He, Takamichi Ichinose, Seiichi Yoshida, Conference on Environmental Pollution and Public Health . 2012

机译：北京城市颗粒增强抗原诱导的小鼠气道嗜酸性粒细胞炎症
5. Biomarkers of Airway Inflammation and Oxidative Stress Regulated by Exposure to Swine Production Environments [D] . McClendon, Chakia J. 2016

机译：暴露于猪生产环境对呼吸道炎症和氧化应激的生物标志物的调节
6. Pathophysiology of Childhood Asthma: 522 Association between Eosinophilic Airway Inflammation and Persistent Airflow Limitation in Asthmatic Children [O] . Yong Ju Lee, Hyun Hee Lee, Kyung Won Kim, 2012

机译：儿童哮喘的病理生理学：522哮喘儿童嗜酸性气道炎症与持续气流受限之间的关系
7. Vitex rotundifolia L. prevented airway eosinophilic inflammation and airway remodeling in an ovalbumin-induced asthma mouse model [O] . Hyunsu Bae, Youngeun Kim, Euijeong Lee, 2012

机译：Vitex圆形olia L.防止气道嗜酸性炎症和呼吸道重塑在卵巢蛋白诱导的哮喘小鼠模型中

25-Hydroxyvitamin D, biomarkers of eosinophilic inflammation, and airway remodeling in children with newly diagnosed untreated asthma

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