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4-oxy-3-(aryl)phenyl-azaryl or -arylcarbonyloxy compounds useful for the treatment and prophylaxis of inflammation diseases of the airways e.g. asthma, these compounds are selective inhibitors of PDE 4 isoenzyme activity
4-oxy-3-(aryl)phenyl-azaryl or -arylcarbonyloxy compounds useful for the treatment and prophylaxis of inflammation diseases of the airways e.g. asthma, these compounds are selective inhibitors of PDE 4 isoenzyme activity
A (4-alkoxy-3-(aryl or azaryl)phenyl)-azaryl or -arylcarbonyloxy compound, in free or pharmaceutically acceptable acid addition salt form, for use as a pharmaceutical. A process for the preparation of these compounds is also described. These compounds are useful in the down regulation of TNF-alpha release, inhibition of PDE 4 isoenzyme activity, effecting immunosuppression, treatment of inflammatory disease, treatment of airways hyperactivity, and effecting bronchodilation.
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